ID A0A182UEB6_9DIPT Unreviewed; 750 AA.
AC A0A182UEB6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles melas.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34690 {ECO:0000313|EnsemblMetazoa:AMEC018848-PA, ECO:0000313|Proteomes:UP000075902};
RN [1] {ECO:0000313|Proteomes:UP000075902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM1001059 {ECO:0000313|Proteomes:UP000075902};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles melas CM1001059_A (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEC018848-PA}
RP IDENTIFICATION.
RC STRAIN=CM1001059 {ECO:0000313|EnsemblMetazoa:AMEC018848-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A182UEB6; -.
DR STRING; 34690.A0A182UEB6; -.
DR EnsemblMetazoa; AMEC018848-RA; AMEC018848-PA; AMEC018848.
DR VEuPathDB; VectorBase:AMEC018848; -.
DR Proteomes; UP000075902; Unassembled WGS sequence.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12301; SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED; 1.
DR PANTHER; PTHR12301:SF11; SHAL K[+] CHANNEL INTERACTING PROTEIN, ISOFORM I; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 365..426
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 452..512
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 119..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 328..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 79004 MW; 00841C3F32126093 CRC64;
MVKGLRFMPS SNRSILRDIR QGLLQLSRDS RDDTYMYDDA VTNVMRMPHH QGHWYDEPPY
ESDPDDFLMS GMRQIGATGY AGDGGGGGDG GGGPSATIQG GRVCYTTNGR EGPQSVISLR
SAGDISIPQR GPRRGLIVPQ QPPNPPTIIP LKHARSHDRE SGDYAGSISD LHSVTSRLSQ
VSIGMNNCTA RYRTLSAGLG DESPSPSPTP SSEYDDILQA NALQLQKHLH HHQQLKRLDG
GMVGPGQPGS TSGLIGSAAS CLVGPAGSSA AVAAAAPVGN SSVGNTSGTS NDARTSPKDH
LLYGGKDRSN RDYSNCLDSI SDQTFQHSAS SVESLPSASG SSTQALVRPG SPHSSLSAED
RTTMLPICRA IALVDSCPSP YDKEALRFKK GDIIDVLSMN ASGVWRGYAN GRLGHFKFIS
VEVLPDLPTT GLKGYGGKLV SRHRLPTSCP TSVEELLLRI GLKEYTSVFV LNGYEDLELF
KELEPSDLDY LGIGNTEHRA KILAAVQLLH DLDSTSDGDV AGSSSENDEG LRLNHIGGLV
GSGVGSGNGS NGGGGDHQTS PFGRRHFTRD SGCYEGSPVP SSQGSHNSHS YQQQLHHLQQ
QHQQQLQSHN NGQPLQPLQQ QQQPHGNMAT LMGTHHHHLH HHHLSDNETN NLDSVVAQCS
NEILKRVESA RRYNGTTERG SSKTMNSRTM AKKGGLLGGG GSDGSGGMVM VGGGGVTGGS
SGGALSEKSS DSGVSSSSLS SGPAKGSGGL
//
