ID A0A182UM21_ANOME Unreviewed; 318 AA.
AC A0A182UM21;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Ionotropic glutamate receptor L-glutamate and glycine-binding domain-containing protein {ECO:0000259|Pfam:PF10613};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM000194-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM000194-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM000194-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A182UM21; -.
DR STRING; 30066.A0A182UM21; -.
DR EnsemblMetazoa; AMEM000194-RA; AMEM000194-PA; AMEM000194.
DR VEuPathDB; VectorBase:AMEM000194; -.
DR VEuPathDB; VectorBase:AMEM21_002574; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF24; IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 219..312
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|Pfam:PF10613"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 36089 MW; 99391DBA8E8FB6AD CRC64;
MVHIGPGPTP DRNEQEHERF SSTLRQSLEF HQFVLLDMAC ENAPDVLKQA SRYELFNASF
HWLIIDNHYN SVEEEGTTGE NGLFTCPWTM ITNSTENGET AKPIQSFTNG TEPDGAMDSD
WTASSNGSEA TASGHTFDLL ATMNVSINAE ITVASPTDPS YRGFTLYDLW NPGFISGGKL
KIEPLGCYSP AKGLQIPKRE STVVRRRNMD GLRLKIMTVV TQKPHQPFEL YLTTPQNTHL
DSVHRYNYGL MGMLKEFYNF TFVNRRTKSW GYLRNGKFDG MIGALSRREV DLGGSPMFFR
QERHRVVSYT TRTFVERI
//
