ID A0A182URT1_ANOME Unreviewed; 680 AA.
AC A0A182URT1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=Cationic amino acid transporter C-terminal domain-containing protein {ECO:0000259|Pfam:PF13906};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM002518-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM002518-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM002518-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A182URT1; -.
DR STRING; 30066.A0A182URT1; -.
DR EnsemblMetazoa; AMEM002518-RA; AMEM002518-PA; AMEM002518.
DR VEuPathDB; VectorBase:AMEM002518; -.
DR VEuPathDB; VectorBase:AMEM21_015404; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 2.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR029485; CAT_C.
DR PANTHER; PTHR43243:SF89; CATIONIC AMINO ACID TRANSPORTER 4; 1.
DR PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF13906; AA_permease_C; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 565..615
FT /note="Cationic amino acid transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13906"
FT REGION 426..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..469
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 72830 MW; 7340165A8B496F4B CRC64;
MPSARRMILG HVMSGLCTKM NRTKQLPADL METPLNRCLN TFDITLLGIG HMVGAGIYVL
TGTVAREMAG PAIVLSFILA GLVSLLAALC YAEFGTRVPK AGSAYVYTYV SIGEFWAFVI
GWNIILEHML GAASVARAWS GYVDSMLGNI VANITMEITG EMHEQLLAKY PDFLAFFVCI
SYAVALAAGV KATAMINSIL TTVNVVVMAL VVVLGFWYAS PDNWSLPEQG FMPYGFGGVL
AGAATCFYAF VGFDSIATSG EEAKNPSFSI PLATILSLCV VTVGYVLVSA ALTLMIPYNE
INPAAALPDA FGMRGITWAK YAISTGAICG MTTTLLGSLF ALPRCLYAMA SDGLLFSCFG
KVNTKTQVPL LNLALSGICS ALLALLFDLE KLVEFMSIGT LLAYTIVSAS VIVLRYRPIS
VEETVHLAPD TPGTDEEDGG PTLPGSGAPG APGGGIDSSS QSSTIDPSSP TSEMIEIALA
GRLRPQFRWL EPVLGRCEPG VACSGAVLMF CVLSVAVCFQ LENSWDELYN GTWWALGLYG
FLLFCLVACV VVISAHHQNT RGLQFKVPFV PYIPALSIFC NIELMVHLSF LTWLRFFIWL
SIGMLVYFLY GIHNSKEGEL GTSYSMLMST SEAIRGWGST STALGGGTKV TVTKIIKGRI
SRKTAGDRQA IVDDDDDEDS
//
