ID A0A182UTM1_ANOME Unreviewed; 1192 AA.
AC A0A182UTM1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM003420-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM003420-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM003420-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182UTM1; -.
DR STRING; 30066.A0A182UTM1; -.
DR EnsemblMetazoa; AMEM003420-RA; AMEM003420-PA; AMEM003420.
DR VEuPathDB; VectorBase:AMEM003420; -.
DR VEuPathDB; VectorBase:AMEM21_008979; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00590; RRM_SF; 5.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23003:SF3; FI21236P1; 1.
DR PANTHER; PTHR23003; RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 4.
DR SMART; SM00360; RRM; 6.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 4.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 5..82
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 90..161
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 279..376
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1036..1109
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 190..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 895..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..223
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..652
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..912
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..936
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..973
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..991
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1004..1020
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1192 AA; 137674 MW; 8028079AC01C1FCA CRC64;
MDPNEVVYIS NIPKQTSLAE LHSFLRSSGN VVGSTFMREN RNDCRTKIAF VLFENEDQAL
EACNLDQTLF QSHRLSVLLS NDDRKFLAGF TIVIQNTSSE TSEEDLFEAC CRYGNVEAVQ
IPTNYYAFVG FAERSAAHAA QRKLDNSMLK GQQVSVKVLD EDVRVRLEDL DSYKTPRVYN
ELLRAKQQYF DNQQPSRGNN QNNRMNHDQD QDQYQDQQHY DNVDDDSMGQ FNQNEDDYDP
SMDQQQDNQQ CFEEEYSPLL VYRRDVRFGK LRFQAANKTS VKVENIPRDV YDEDVVIFFQ
KFGPIVSIER GICLNAVFTK VYMITYENEE SQQRAINCFC RQVVLSNITC TVFTMIPGEA
LYPVKNQSVL INYVPTYVFF DEIVQAFADV GNVLYVEKMV RNNGPTIVHF THPISMTDAC
QINCIAGYTV FIMPVSQKDF QRFVSSCASL KKAAKGKVHG TSKFNYLHDI EAKEEQEKMD
NIIFKTAHNP HYRNPNPNKY SFEVVLYNCP KNMKLTALKQ YFNRAGEVLA MRHETSRYDP
NTWKVYVSFA NYLEAYRAIR LKGKLGGELI FKHIAAESPK LDCVEGIMVK VLTGLKDVLK
QNGFKKGGPG AQLDDVDDVK RRPRVLLSDI FADKEVEDNP PKQQKPPKQE PVKVEVKNAP
SESPKASTSG APPPLSPDAK SDDLRKVIAE KRSSKSECQD KLSDLEEMER YIKQKEQEIQ
RRLQKLERDE ANVTALLPST SSKRQKSPEG KGKDSTSSSS SSRAEQSSSR SKRLSPARSD
SASTSQRIST HTTTATTVSS IPTTYPAGKM MFPDQMRSVS PSDRLAHERY MQIRVEKIAI
TQELDSLRQR FDYRKGSRVD ALRDLLAGLN REQREIQIQL EAKWRFRMPE DVNYAGSSFD
ASPSPPARRQ NVRSRSRSPR RSPRRSPHRS YHRSPYRSLS RSRSPSPRNY GRSRSRSRSR
SRSHGRSRQL TRSRTRSPVR WSRTSRSPSP QFYRQRRRRS RTPSREARPP SEPRRGYSLE
RDMYNIGRYN TKHQKHTVFV GNVSSKMSER EIEEIFARYG RLENVDFARR KRFGEVYFNY
SNRDHAFKAL EMNNVKIMGR RLRVSFNSEK PIHREGYTIY YTMRQPTDEQ TIYQSYESYG
EIDFIWYPEN GLFGTITFRR AESATEALAV NELSDGTTIR PKPFIDKVRH VQ
//
