ID   A0A182UXB8_ANOME        Unreviewed;       632 AA.
AC   A0A182UXB8;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   13-SEP-2023, entry version 28.
DE   RecName: Full=START domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles merus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM005254-PA, ECO:0000313|Proteomes:UP000075903};
RN   [1] {ECO:0000313|Proteomes:UP000075903}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles merus MAF (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEM005254-PA}
RP   IDENTIFICATION.
RC   STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM005254-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A182UXB8; -.
DR   STRING; 30066.A0A182UXB8; -.
DR   EnsemblMetazoa; AMEM005254-RA; AMEM005254-PA; AMEM005254.
DR   VEuPathDB; VectorBase:AMEM005254; -.
DR   VEuPathDB; VectorBase:AMEM21_008525; -.
DR   Proteomes; UP000075903; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   Gene3D; 3.30.530.20; -; 2.
DR   InterPro; IPR019498; MENTAL.
DR   InterPro; IPR000799; StAR-like.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR46121; STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE; 1.
DR   PANTHER; PTHR46121:SF4; STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE; 1.
DR   Pfam; PF10457; MENTAL; 1.
DR   Pfam; PF01852; START; 2.
DR   PRINTS; PR00978; STARPROTEIN.
DR   SUPFAM; SSF55961; Bet v1-like; 2.
DR   PROSITE; PS51439; MENTAL; 1.
DR   PROSITE; PS50848; START; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        87..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          81..256
FT                   /note="MENTAL"
FT                   /evidence="ECO:0000259|PROSITE:PS51439"
FT   DOMAIN          269..620
FT                   /note="START"
FT                   /evidence="ECO:0000259|PROSITE:PS50848"
FT   REGION          393..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          499..525
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        399..413
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   632 AA;  70084 MW;  031C08DCF4D9784D CRC64;
     MAEEDEIRTA VHSFYTIQQQ QQQLQQSAHT PVVHHPFMMH GPRGYGSGPP MNALAMTRSQ
     SHTVNLLSED FIAGYMEQGR MSVVRRFFCL FVTFDVVFIS LLWIICVVIT GDNVIHALQT
     QVLHYTVYTS LFDVVIAALI RFIFLILFYG LLSISHWLVI ALSTTSSCAF LISKVFLYDW
     TATPQPVFEV LLIVVSFVLA WGEAWFLDCR VIPQERYARN YFVGGQECTL GSGNLKAVLP
     VWINRSVRKD DEFKKMGTEC VRKAYMLLES DGWKIEKVTA KGDTIQSCQQ EKIGKIYKLT
     AKIHYPARKL LQELFYKIED VPKWNPTLLE SKIIRKIDSH TDISYQATIG GGGGVVKCRD
     FVNLRCWHLC RDGRVIEGVD ILPNPLINLS PVTEECEGNG SVGGQSDESG EESSVGSIGK
     GDVSGRIPAS KSVPQMSQSH GELKTDGPAA GAADGSEQKD KTAFKTLSKS LGAQDFAAGA
     GGGGAVSDEN EDVFSDALTD DQEGKAASVK PVEGSAKKKR NVAREEAEST AKCSNVYVSA
     AISIDYPGAP QNTKYIRGEN KVSCWAMREL ENQKDHCIFE WLLCLDLKGY IPRYVLDTAY
     TTLMQDYMTY LRKYVAELRK QGKVPGGPES TA
//