ID   A0A182UXD9_ANOME        Unreviewed;       808 AA.
AC   A0A182UXD9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=PWWP domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles merus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM005277-PA, ECO:0000313|Proteomes:UP000075903};
RN   [1] {ECO:0000313|Proteomes:UP000075903}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles merus MAF (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEM005277-PA}
RP   IDENTIFICATION.
RC   STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM005277-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182UXD9; -.
DR   STRING; 30066.A0A182UXD9; -.
DR   EnsemblMetazoa; AMEM005277-RA; AMEM005277-PA; AMEM005277.
DR   VEuPathDB; VectorBase:AMEM005277; -.
DR   VEuPathDB; VectorBase:AMEM21_014535; -.
DR   Proteomes; UP000075903; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR   GO; GO:0034243; P:regulation of transcription elongation by RNA polymerase II; IEA:InterPro.
DR   CDD; cd05492; Bromo_ZMYND11; 1.
DR   CDD; cd20159; PWWP_BS69; 1.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR047268; PWWP_BS69.
DR   InterPro; IPR000313; PWWP_dom.
DR   InterPro; IPR047269; ZMY11.
DR   InterPro; IPR002893; Znf_MYND.
DR   PANTHER; PTHR46379; ZINC FINGER MYND DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR46379:SF1; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SMART; SM00293; PWWP; 1.
DR   SUPFAM; SSF47370; Bromodomain; 1.
DR   SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR   PROSITE; PS50812; PWWP; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00134}.
FT   DOMAIN          457..502
FT                   /note="PWWP"
FT                   /evidence="ECO:0000259|PROSITE:PS50812"
FT   DOMAIN          764..798
FT                   /note="MYND-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50865"
FT   REGION          150..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          254..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          586..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..177
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..641
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        642..661
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   808 AA;  91189 MW;  E425030D07480376 CRC64;
     MASLVQQETP CGVISAIWNI ITSAQGEEIE QTKLVEQLAD VLEDTELAER HVQAAISDEL
     IVECARPKHR GRQRLTPTYT VPANWQTYAI PEGQPDKYCY ECHHVGSVVK CAGCVRSLHE
     GCLKTGDERQ LELEQYMSKQ KRITVSAVKA RTARGRQRRS SAASLAVTEE STVSSMDLSA
     AQGSVELADS TGLGQHGSAD DSVDVMVSES LADRIKHESD DACSSIKREE NVKEEGLPTV
     DDAMFVGMVR PPNRRLERSL NTPTVKPEVS EREGSAGRDG SDNSSQAASD TIAPRYCYAC
     ELLRYSSNQA PSSIEKSELN YLLKFVVEQY KSWIPKDTFS TSKFLRDTAR HTPVVTRKTI
     DICRKMLLRI PTSFADVREK IASKQYARLE EFHVDLLDIV HNVAIIHGDT SMAYSAAMYF
     LADCVYDLRE IRHCSDCYRH SAEKAEPDWF ARPCRTRHEL VFAKQSRFQY WPAKVVRVVN
     NLYDVRFFGG NHPRALIDAG WVKPIDTELG TLGVKDKHGG FQLAMKEMLK YQSLAEGFRD
     HFAFTSVTEQ MQAAVVARTV ESVLPPELRE GAGRQSTSLG FEFAARTTKK RQRNQRNKQP
     SVVHQSVPLG AVSPPPTVAS TKGSTISTRS KRRETASHQH TPAKKTRSST QAVAQSPEQD
     SVELPLQQLD CALDSNHNGY DGEVGASSST RVARTKQNEI LRFPEKYDTF RLKQLFQQVT
     DLEETKQVAL KLLQNKEQHF ARKLEWLKET HQHQISEIKK RQWCVVCEKE ARIPCCWNTS
     YCTTDCRERH WPGHQRQHPI ESHSNRFS
//