ID A0A182V0F9_ANOME Unreviewed; 1289 AA.
AC A0A182V0F9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Ig-like domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM006782-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM006782-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM006782-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR STRING; 30066.A0A182V0F9; -.
DR EnsemblMetazoa; AMEM006782-RA; AMEM006782-PA; AMEM006782.
DR VEuPathDB; VectorBase:AMEM006782; -.
DR VEuPathDB; VectorBase:AMEM21_003220; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 10.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF08686; PLAC; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 9.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00209; TSP1; 10.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 9.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS50092; TSP1; 8.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 794..877
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1250..1287
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT REGION 13..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..958
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 959..982
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 58..89
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 62..94
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 73..79
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 1289 AA; 142752 MW; DFFDB52C204B26DC CRC64;
CLILTLAKAT HKDNRGGSNE TLSTWSPSGV DLEDEDDEEV QKRAKAQGWS SWTEWSTCSR
SCDGGVAYQL RRCHAPHGCK GDAVRYKICN MQPCPEQQDF RAHQCSAYDD VPYDGALLKW
TPHYDYSEPC ALTCRGRPQH LLEDMPDSAG AGDSFPISDD EPSVIVQLSN RVQDGTRCRP
GSLDMCIQGK CQRVGCDLKI GSTKKIDVCG VCGGDGTSCT QPLYQWEIAP MSLCSVTCGG
GYKMAMPTCR NRVTGVDVEE SLCNASSRPE PTVVQCNTHL CPPKWVTDDW RSCSKPCGGG
IRERVVVCAE ESNGAKNKVP DEACRGVRPK NQEPCNVQEC PKWVVGEWSG CSVSCGSGIQ
VRSVECMDTN GHYSAQCDPG AKPVTGQPCT TGIICNAGSV SSGLSGGANT GTTVSGSSNA
GIIAVPPSSA SDFDGLTMGV ESEAERASIS AMMKEKAAMH HERDPTLMTY NDQPYYAQPL
RQDRLPKAEK IVSQRVPSEA TFIQDTEWSP CSVTCGEGIR RKPFRCKIFL EFSKRVAVLN
DSLCHAYKPL DEVERCVMEP CSYSHNFEDT YLKDGNRQSL ENIKVHVSVP GKTYSWREEG
YTSCSASCLG GVEELIINCV RDDTNKIVSP FLCSPETKPE ARIRTCNDIP CPPRWNYSEF
TPCSKSCGFG IQTREVTCIH EVTRGGENTM IVPNSMCTTK PQPDRQYCNI IDCPVRWEVS
EWSKCSKSCG GGFKERRVEC KQIMAQEHKV ERPASMCPSS KPPDKKPCNT KACAPEDQRP
PIAGTNSTFI QHDPKKNKIT LKIGGAATVF YGTQVKIKCP VKRFNRTKIR WTKDQQPLLK
TKKIKMSKKG ALRILDVTFR EAGIYTCHAG LSHADLKLAV KAKPGGENQP NEDHDRHRGA
DPNALLANSY AMANGNEEEK SGRKNRDRNR GRNRQRQQQD TLLTEHGDGS DDEEPLRSHS
QMTVSGSTVA SDASAAASSG TRTLPLPHFQ HLLAGLQTFS NSKNYGQQYL AERGYDPFDG
SIGRGDVEDE EPPRPMNVYQ LLKSRHTSES VDEPMIHDGQ ATEGYEFEWM TTPWSECSQT
CGANGGGYKL RSAHCMLRMS NSSRTVDNSF CEDAGLPVPE TVDKCGNIDC PRWVTADWSG
CQQSKCFSWH TALQRRDVYC QFDGERSDEK VCEDQEKPVT KQECYNELCK GVWRVEPWSD
CNAACEGQGI KYRILQCVWY GTKKPAGSAC RELPRPAVMK VCKGPPCISN LSECKDLSRY
CKNVKSMGLC RLHRYQQQCC KTCRFNIYH
//
