ID A0A182V1H0_ANOME Unreviewed; 1025 AA.
AC A0A182V1H0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM007282-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM007282-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM007282-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; A0A182V1H0; -.
DR STRING; 30066.A0A182V1H0; -.
DR EnsemblMetazoa; AMEM007282-RA; AMEM007282-PA; AMEM007282.
DR VEuPathDB; VectorBase:AMEM007282; -.
DR VEuPathDB; VectorBase:AMEM21_010135; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF713; UNCONVENTIONAL MYOSIN ID; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}.
FT DOMAIN 9..692
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 808..1005
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 569..591
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 102..109
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1025 AA; 118280 MW; D72BA3F819ABF8AA CRC64;
MAHHQGQEVG VQDFVLLDAV TQDKFMDNLK RRFQAGKIYT YIGEVCISVN PYREMNIYGP
EYVNRYKGRE LFENAPHIFA IADAAYRVLK QRNNDTCIMI SGESGAGKTE ASKIIMKYIA
AVTNQGKQGE IERVKNVLIK SNAILECFGN AKTNRNDNSS RFGKYMDIEF DYKGDPVGGI
ITNYLLEKSR VIQQQSGERN FHCFYQLLRG GANNELQQYN LGRDPAAYHY TNQGSTEILS
EKSDYRATTG GLQALGFSAE EISMVWRTVA AILHLGNIEF KMKDEKITIA NGKTLANVAQ
LLQVTAEEMR SALTERVIAA RGEIMTKSHD TKQAEYGRDA LAKAIYDRMF TWIIQRINKA
IVVPGSTTQK RYNKVIGVLD IYGFEIFDRN SFEQFCINYC NEKLQQLFIE LVLKQEQEEY
NREGIEWTNI EYFNNQIICA LVEQADKGVI AIMNEACLNV GKITDEMLLG DMDKKLSHHP
HYSSRQLKPM DKELRHKEDF RITHYAGDVI YSISGFIEKN RDTLFQDFKR LLYGSHDKVI
SSMWPEGAQD IAKTTKRPLT AGTLFQKSMA ELVATLLRKE PLYVRCVKPN DIKSPTVFDD
VRVEHQVRYL GLLENVRVRR AGFVHRQRYD KFLLRYKMIS QYTWPNFRGG NDREGVKVLM
NEKNFSHDVR FGKTKIFIRS PQTLFALEQQ RNDMIPHIVT LLQKQVRGWI TRQKYKKMKA
ALVIMRHYRK YKLKSYVQDL AVRFRNARTL RDYGKGIQWP QPPLVGRQAE RQLRMLYSRW
RAAMILRKYP REEWPQLRLQ IIAASAFRKR RKCWGHDRRW LGNYLSIVAE NSNYSSYNAS
VRNIKNVDNF DTIVFSAFVK KFNKCNKSAD RAIIVTDGTI YKLDGPKNKF RNMKRTVAIR
EITSISVSPG RDQLAVFHSH HNNDLIVSLQ GEHQPLKEDR IGELVAHVIR RYFAICQQEL
PVNVASTIPL RLGNKSRSLS IEAAAGQDMP EFTHAGTFII FKVPAAYASA QETTETSPNT
LPQRY
//
