ID   A0A182V1T2_ANOME        Unreviewed;       291 AA.
AC   A0A182V1T2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00039666};
OS   Anopheles merus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM007432-PA, ECO:0000313|Proteomes:UP000075903};
RN   [1] {ECO:0000313|Proteomes:UP000075903}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles merus MAF (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEM007432-PA}
RP   IDENTIFICATION.
RC   STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM007432-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC       {ECO:0000256|ARBA:ARBA00007958}.
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DR   AlphaFoldDB; A0A182V1T2; -.
DR   STRING; 30066.A0A182V1T2; -.
DR   EnsemblMetazoa; AMEM007432-RA; AMEM007432-PA; AMEM007432.
DR   VEuPathDB; VectorBase:AMEM007432; -.
DR   VEuPathDB; VectorBase:AMEM21_007743; -.
DR   Proteomes; UP000075903; Unassembled WGS sequence.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006357; HAD-SF_hydro_IIA.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR006355; LHPP/HDHD2.
DR   InterPro; IPR002645; STAS_dom.
DR   NCBIfam; TIGR01458; HAD-SF-IIA-hyp3; 1.
DR   PANTHER; PTHR19288; 4-NITROPHENYLPHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR19288:SF46; HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF13344; Hydrolase_6; 1.
DR   Pfam; PF13242; Hydrolase_like; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
FT   DOMAIN          1..107
FT                   /note="STAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50801"
SQ   SEQUENCE   291 AA;  32517 MW;  66899BC811E6F171 CRC64;
     LDFPAKCLVC WFIFFFGPFH RPTTQMAVLR VKLALIDLSG TLHVDDQPTV GAVEALKRLR
     QHGVQVKFVT NTTKESVGSL YDRLRKIGFE LQRDEIYGSL GAAAEYVRRN NLNPYYLLTD
     DARTDMPPND PERALDSVVV GLAPERFCYE HLNEAFRVLH QRSVKQQVQL VAVHEGRYYK
     AKDGIALGPG CFVKGLEYST GVPAVCIGKP NEYFFRSALP DGIDVAECVM IGDDPNDDCL
     GAMRIGMKGY LVETGKYQPE KYTDEDRPAV SGIFPTFSDV VQHIISSSAE Q
//