ID A0A182VBT9_ANOME Unreviewed; 555 AA.
AC A0A182VBT9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 03-MAY-2023, entry version 30.
DE RecName: Full=Cytokine-like nuclear factor N-PAC {ECO:0000256|ARBA:ARBA00034140};
DE AltName: Full=Glyoxylate reductase 1 homolog {ECO:0000256|ARBA:ARBA00030287};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM012305-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM012305-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM012305-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
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DR AlphaFoldDB; A0A182VBT9; -.
DR STRING; 30066.A0A182VBT9; -.
DR EnsemblMetazoa; AMEM012305-RA; AMEM012305-PA; AMEM012305.
DR VEuPathDB; VectorBase:AMEM012305; -.
DR VEuPathDB; VectorBase:AMEM21_012367; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05836; PWWP_GLYR1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR035501; GLYR1_PWWP.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454}.
FT DOMAIN 9..70
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 127..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 60323 MW; 62DB4F31FCEAC9B3 CRC64;
MSDSTGYAVN DLVWAKMKGF SPWPGRISVP PAELRKIAVK KNNPVKCIFF FGSNNYAWIE
ETQIKPYLQF KDTHLNSSKS AQFKEALKQI EEFRVNPEKF QPLFVGENEA ANRPDPDEEF
NRLREGVASG TEESGAEDGA SVNNTTTPAV LESVDEATST PMVKKSAKKK VRASLPIKLN
VDKVPRSVGN KAKAMLDDGV SGAPSPKRKK KLLNDSGELS SLDASPVRRN APVTHLLNRP
VTVTRPETPE IDMSSVSNAV QSRNIKASQL KFGFLGLGVM GCGIVKNLIK SGHSVVVWNR
SAHKCRKFQE VGAEVADTPS DVVEMTDVTY SCVSDPQVAK DMVFGNCGVM SANLAGKGYV
EMTGVDPETS NDINEAIISK GGRYLEAQIQ GSKNQAEEGT LIILASGDRL LFEECQSCFE
AISRNSFYLG DVGNATKMNL ILQMISGITL AGVAEAMALA DRAGLQQKDV LEVLELTNMS
SEMMLQKGNA IIKGEFPTHQ ALKHMQKDLK LALSLADGLE QSLPITAASN EVYKHAKRLG
YGSHDASAVY VRARF
//
