ID   A0A182VGF9_ANOME        Unreviewed;       417 AA.
AC   A0A182VGF9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 25.
DE   RecName: Full=W2 domain-containing protein {ECO:0000259|PROSITE:PS51363};
OS   Anopheles merus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM014563-PA, ECO:0000313|Proteomes:UP000075903};
RN   [1] {ECO:0000313|EnsemblMetazoa:AMEM014563-PA, ECO:0000313|Proteomes:UP000075903}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM014563-PA,
RC   ECO:0000313|Proteomes:UP000075903};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles merus MAF (V2).";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMEM014563-PA}
RP   IDENTIFICATION.
RC   STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM014563-PA};
RG   VectorBase;
RL   Submitted (OCT-2016) to UniProtKB.
RN   [3] {ECO:0000313|EnsemblMetazoa:AMEM014563-PA}
RP   IDENTIFICATION.
RC   STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM014563-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the BZW family. {ECO:0000256|ARBA:ARBA00008151}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A182VGF9; -.
DR   STRING; 30066.A0A182VGF9; -.
DR   EnsemblMetazoa; AMEM014563-RA; AMEM014563-PA; AMEM014563.
DR   VEuPathDB; VectorBase:AMEM014563; -.
DR   VEuPathDB; VectorBase:AMEM21_002821; -.
DR   OrthoDB; 5475947at2759; -.
DR   Proteomes; UP000075903; Unassembled WGS sequence.
DR   CDD; cd11560; W2_eIF5C_like; 1.
DR   Gene3D; 1.25.40.180; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR043510; W2_BZW1/2.
DR   InterPro; IPR003307; W2_domain.
DR   PANTHER; PTHR14208; BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR14208:SF2; PROTEIN KRASAVIETZ; 1.
DR   Pfam; PF02020; W2; 1.
DR   SMART; SM00515; eIF5C; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51363; W2; 1.
PE   3: Inferred from homology;
FT   DOMAIN          244..415
FT                   /note="W2"
FT                   /evidence="ECO:0000259|PROSITE:PS51363"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..29
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   417 AA;  48396 MW;  73FC7B6A61905A38 CRC64;
     MSQKAERPVL SGQRIKTRKR DEREKNDPTG FRDAVIAGLD AAEDLEQIYK YLDSAGNKLD
     YRRYGEVLFD ILIAGGLLVP GGSISQDGEK PRTDRCIFAA SEDMESMRNH EQIFMRLMRR
     YKYLEKMFEE EMKKILIFIK GFTPLERIKL ARMTALWMAN GSIPPQVLSV LNNEHLTKDG
     LALEFLLEVF VTYKQEKGGN APLVAALRKS GLDNRLLEFL PLNKRNEDYL KTVLVEKDLA
     DIFKLHMNQA SQEAKRELTQ LLVDDINDNK TIKDIIADTK EMSTKSNIPE HEVVGLIWST
     VMSLAEWNKK EELVTEQATK HLRTYTPLFE AFTTTDRSEM ALLLKVQEFC YENMNFMKAF
     SKIVLLFYKT EVITEDSILK WYKEGHSNKG KMHFLEQMKK FIEWLQNAEE ESESEED
//