ID A0A182VJG0_ANOME Unreviewed; 837 AA.
AC A0A182VJG0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 13-SEP-2023, entry version 33.
DE RecName: Full=Actin-binding lim zn-finger protein limatin involved in axon guidance {ECO:0008006|Google:ProtNLM};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM016003-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM016003-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM016003-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182VJG0; -.
DR STRING; 30066.A0A182VJG0; -.
DR EnsemblMetazoa; AMEM016003-RA; AMEM016003-PA; AMEM016003.
DR VEuPathDB; VectorBase:AMEM016003; -.
DR VEuPathDB; VectorBase:AMEM21_012423; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF9; UNCOORDINATED 115A, ISOFORM B-RELATED; 1.
DR Pfam; PF00412; LIM; 4.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 4.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 3.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 4..63
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 64..123
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 207..266
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 772..837
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 159..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..569
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 93191 MW; 131653EC1E1C3CA9 CRC64;
KSKIQCSKCQ KKCSGEVLRV SDRYFHKTCF QCTKCNKSLA TGGFFSKDGA YYCTLDYQKL
YGTKCAACSQ YVEGEVVSTM GNTYHQKCFT CSKCKQPFKS GSKVTNTGKE VLCESCVKCP
PGSGVGGGGG ATATGSPTVG AAAGVVQGTG SATVSPKSRA IEQKQEQRTI KEITSSPTKA
ATLQHHQETV KKQQQLLQNG GKQPDPNDCA GCQQQLKEGQ ALIALDRQWH IWCFKCNACG
TTLNGEYMGK DGVPYCEKDF QKSFGVKCAH CNRYISGKVL QAGDNHHFHP TCARCTKCGD
PFGDGEEMYL QGGAIWHPRC GPGPSSEAGI LNGVDTNGFN TETEFDRTST SGMSEIQVSE
EEGEEGTRGD EMCFLCYHRT TSPGLILREY KNQGYEDIAR IYTYSYLTEE PGYLRRPIEP
YDRAPVSPHF HRPVQHYSSM GGGTASSIGT RSASGSRSHS RSRSAMKVLV DSIRSETPRP
KSPGMNNEEP IELSHYPAAK KPPPGEKPKI ERDDFPAPPY PYTDPERRRR YSDSYKGVPE
SDDEVDHANN KENVTEKRHT KEEEELRKLK SSGMGTVILK DLQEKKRYEH WKQENLDPRN
ASRTPSASKE PMYRMRYESP VGASPSRNLD HQKPFYEDEF DRSTSYRGSV GRAIGNATSY
NGKQNGRGTA IHSYRSPPKP GYGFKTSTLP PSLRNGYSSD FSFSGLGDKT HSTEFSCGKS
DISGDSITEG DRRALGAELP ASSTYSGALS YHYPQQPTRR SLPNMAHSML VHEPAKIYPY
HLLLITNYRL PSDVDRCNLE RHLSDVEFEA ILQCTRPEFY RMPQWKRNDM KRRARLF
//
