ID   A0A182VRZ9_9DIPT        Unreviewed;       620 AA.
AC   A0A182VRZ9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
OS   Anopheles minimus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN000840-PA, ECO:0000313|Proteomes:UP000075920};
RN   [1] {ECO:0000313|Proteomes:UP000075920}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMIN000840-PA}
RP   IDENTIFICATION.
RC   STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN000840-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC       {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the ninjurin family.
CC       {ECO:0000256|ARBA:ARBA00008141}.
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DR   AlphaFoldDB; A0A182VRZ9; -.
DR   STRING; 112268.A0A182VRZ9; -.
DR   EnsemblMetazoa; AMIN000840-RA; AMIN000840-PA; AMIN000840.
DR   VEuPathDB; VectorBase:AMIN000840; -.
DR   OrthoDB; 3472466at2759; -.
DR   Proteomes; UP000075920; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0042246; P:tissue regeneration; IEA:InterPro.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR   InterPro; IPR007007; Ninjurin.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24408:SF58; LINKING IMMUNITY AND METABOLISM-RELATED; 1.
DR   PANTHER; PTHR24408; ZINC FINGER PROTEIN; 1.
DR   Pfam; PF04923; Ninjurin; 1.
DR   Pfam; PF00096; zf-C2H2; 3.
DR   SMART; SM00355; ZnF_C2H2; 8.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   TRANSMEM        500..522
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        529..552
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        572..595
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          270..298
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          328..355
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          356..383
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          384..411
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          412..436
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
SQ   SEQUENCE   620 AA;  70131 MW;  78F1E11DCBAAFD85 CRC64;
     MNSPAGREKC GICGTHSLIF HPNLMAVKTK FSSTTVFQLL ERFTERELSH QVAYLEESGV
     CNDCLAKLND YDAAYTKALI IQQELTDLLQ NGPKWYAEVE QELDVANEEE DIRKHKGLGI
     KWVPHLERPG AIEGHGKKKQ AFSIAGLSTV RVSMKCNVCG ELFNNIHAMK LHSHDEVGEE
     DQLETLARES PSSAPSPTLV IETVKSEPTS SVNSDYDADE YIDYTINMLN AKDEEDEASA
     VDEYCTTENN AEKESNEQSE QNNEKIDVPY VCCLCEAKFE SKLELKAHFK TDHPNNTEGN
     VCKVCGISTR TRAALASHYG KHLRESQLTC LLCNKKFTQR GSLQRHMAIH TGEKTYQCDL
     CGKQYLHYSS FYMHQLAHRN VRSKKCTICG YTLRSNSHLK RHMRTHSGEK PFACPVCGQK
     FSQRYNMVQH QKTHKGILGR SAKTFSCPSC DYISDRSALM KKHMLKHHGM ECMELAESPE
     TKETLVRNDD TKRKSPLGNM FVQSMFDMTL ITINFCQICY ILKVGPGLGW LYYFLLGLFG
     VSLILLFMHG LMGLCGRLRC SKPLPTSCFN CLYNASMFMV VVVYMVNLVG SVLMLKEAEN
     KCQLMLEHTK SIMTPVLETP
//