ID A0A182VZC7_9DIPT Unreviewed; 391 AA.
AC A0A182VZC7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Vacuolar H+ ATPase AC45 accessory subunit {ECO:0008006|Google:ProtNLM};
OS Anopheles minimus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN003432-PA, ECO:0000313|Proteomes:UP000075920};
RN [1] {ECO:0000313|Proteomes:UP000075920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMIN003432-PA}
RP IDENTIFICATION.
RC STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN003432-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC {ECO:0000256|ARBA:ARBA00009037}.
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DR AlphaFoldDB; A0A182VZC7; -.
DR STRING; 112268.A0A182VZC7; -.
DR EnsemblMetazoa; AMIN003432-RA; AMIN003432-PA; AMIN003432.
DR VEuPathDB; VectorBase:AMIN003432; -.
DR OrthoDB; 2878970at2759; -.
DR Proteomes; UP000075920; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.160.110; -; 1.
DR InterPro; IPR008388; Ac45_acc_su.
DR InterPro; IPR046756; VAS1/VOA1_TM.
DR InterPro; IPR046755; VAS1_LD.
DR PANTHER; PTHR12471:SF4; AGAP001624-PA; 1.
DR PANTHER; PTHR12471; VACUOLAR ATP SYNTHASE SUBUNIT S1; 1.
DR Pfam; PF20520; Ac45-VOA1_TM; 1.
DR Pfam; PF05827; VAS1_LD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..391
FT /note="Vacuolar H+ ATPase AC45 accessory subunit"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008140472"
FT TRANSMEM 347..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 196..325
FT /note="V-type proton ATPase subunit S1 luminal"
FT /evidence="ECO:0000259|Pfam:PF05827"
FT DOMAIN 341..378
FT /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF20520"
FT REGION 159..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 43488 MW; 19535589F920570D CRC64;
MFLRVQLLAL ALAVTLVQSS SAYYSGPFLF WGLDDLKDLQ TPALTEVDDK MLRDLYSNAA
AVVVFLRNGT TKLSADNFPT FKRIVEKYEF MYSPQQMLSS NPLDYNVNAE VINLVGSPSQ
QDVELSALFR DSTENYGERK VLGILANQWE EPHVLHKREA KGGEEMYSTS STTPGSPTDE
PEIADSIYNV PGKAILYMTG PPVLKMLNDS DEGETTHVLD KHTLATYDAR ERESKMIVTF
KVDDSTKLTL KFRFDMDAGY WSMSKVDVFV MDTKSKDGAK SLDTTLELEG KAPYAPLGAS
YSCARQLVFR NGTTVLTLEN IQVQPALEGK TKFDSAWDCV GFTTAPILSG IFVTSFMLIG
LTIAIIAILD IKTPNRFESR TGKQLTFTVQ E
//
