ID A0A182W0W0_9DIPT Unreviewed; 705 AA.
AC A0A182W0W0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
OS Anopheles minimus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN003969-PA, ECO:0000313|Proteomes:UP000075920};
RN [1] {ECO:0000313|Proteomes:UP000075920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMIN003969-PA}
RP IDENTIFICATION.
RC STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN003969-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A182W0W0; -.
DR STRING; 112268.A0A182W0W0; -.
DR EnsemblMetazoa; AMIN003969-RA; AMIN003969-PA; AMIN003969.
DR VEuPathDB; VectorBase:AMIN003969; -.
DR OrthoDB; 1334125at2759; -.
DR Proteomes; UP000075920; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0000012; P:single strand break repair; IEA:InterPro.
DR CDD; cd17725; BRCT_XRCC1_rpt1; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR045080; BRCT_XRCC1_rpt1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002706; Xrcc1_N.
DR PANTHER; PTHR11370; DNA-REPAIR PROTEIN XRCC1; 1.
DR PANTHER; PTHR11370:SF5; FI04011P; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF12738; PTCB-BRCT; 1.
DR Pfam; PF01834; XRCC1_N; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50172; BRCT; 2.
PE 4: Predicted;
FT DOMAIN 449..536
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 620..704
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 283..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 78688 MW; 73014DED580DBA2E CRC64;
MPSVCFKAVE SFSSEDPNYP ASNLLKPSNR KWKCRQPGEQ QAYVVLRLEE PTQITGIDIG
NEHSALIEVL VARSGPSNPS YSEILLATKF MNAVDSRNST GTNGVQCFNS SVLIPSVASD
KWDLVKIICT QPFNSRVRYG LTFVALHTNS GTEKKERKSL VPEKFQQQIR EEANRPKQTS
SVGLNLGRFK LREESPDSDD AGFSNIFTRW KNSITTGSTT AGPTVSALMR DTNTAKALQK
NIPMPGSVRS VAKQRPNTVE FVDSDVEEVN QLANTSVKVN RNDESVLYDA EDDKPTKKRN
ESVTVRSEVE VSKRELTTSK PSAKNASKIS NASSSKFKDF LDLSGSNHTP KRNDERSKSP
SSTPTAARKQ HNSSSLTDRK DTPKKSVDQA RPPLSIEKQT IPSSKRLSSP TKSPSNNHGS
TTPMTKKPKL AIVDVDSDTE VNRPVRYKPF GKLLEHVVLV ISGIQNPDRG NIRSQALAMG
AKYKPDWDAS CTHLICAYKN TPKYNQVHGK GKIVKKDWIE KCYTNRKRLS WRKFALDTAE
ANVSDSEDEI VDIANKPAEV VEPLQIRNTA PPLVEKAQEE AVMLHELSDT DEEPGAIIAR
KVYDKSTEDE GDRYADNVVG SLEFFKGKTF YLHQELGAVD MMKLEKYIET FKGTVSKEMT
GVDYVIARSK HTLPFNSRAE LVKPLWVYEC NDMECLIPVN RYRIV
//
