ID A0A182W7B1_9DIPT Unreviewed; 705 AA.
AC A0A182W7B1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles minimus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN006233-PA, ECO:0000313|Proteomes:UP000075920};
RN [1] {ECO:0000313|Proteomes:UP000075920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMIN006233-PA}
RP IDENTIFICATION.
RC STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN006233-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A182W7B1; -.
DR STRING; 112268.A0A182W7B1; -.
DR EnsemblMetazoa; AMIN006233-RA; AMIN006233-PA; AMIN006233.
DR VEuPathDB; VectorBase:AMIN006233; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000075920; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF5; -; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1..43
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 184..237
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 345..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 105..136
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 354..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 80078 MW; F0BA6E169655B880 CRC64;
MSEFAENLGG NSRTVMLATI SPASIHLDET LATLRYACQA RSIVNRVKVN EDPHDRIIRE
LRAEVERLQV LRQDYERQKR LSEAHQHHHP PRKIIIETSV DDGEVEALRQ QLAETEQELS
KAQRSWRERL QEAEDVRRTE MKLLKRKGLA LELSAEQKEP CLVNLAADPM LSGTLLYIIP
PGTVQIGRPS SLSSPDIVLE GPLVSPNHCS IENKNGKLFL LPETNTEYET FVNGELIVER
RQLFHGDRLV IGGSHYFRIS NPLCPNKSTQ IMVDFQLAHQ EILQEQENRL RRELDAEKQA
AIARIEAERM AHEQEYEERL ASLELEKFKY TCRKELLETE QKALLQSAGG KRSKPDGTKA
RPSDVRDSLD CAPSKVESNL AEKIRQIMEH TSEESLAHIQ MMVKEASQRC RSVGLDYEFK
QTQVWQDEGI FRAMINIVDR ANGRIAEWVP ARLECWLGIV RERDDLTVDN MFEHFDLVWI
DAADRSANES LLQDSHNSSR ISLNLSAVKE AIRGRHSTCS NSSSPSSESC VAGSVRKSQG
LFKSIFSRPT QMQNEDKACP TNSARKALFI DAESNDENVP SNHQHPSPAH QTKGVPTVLH
RFDQKAANYL RDLCLVTLKL RKLCEKQQEF EAPANGDPAQ VQDKQKRNNT DEKLAARCLE
SVADIERSLQ TIRSVLADHN IKEATLNAME DEFGRTPKSV RFLLD
//
