ID   A0A182W8K4_9DIPT        Unreviewed;       911 AA.
AC   A0A182W8K4;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 28.
DE   RecName: Full=Alpha-carbonic anhydrase domain-containing protein {ECO:0000259|PROSITE:PS51144};
OS   Anopheles minimus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN006678-PA, ECO:0000313|Proteomes:UP000075920};
RN   [1] {ECO:0000313|Proteomes:UP000075920}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMIN006678-PA}
RP   IDENTIFICATION.
RC   STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN006678-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182W8K4; -.
DR   STRING; 112268.A0A182W8K4; -.
DR   EnsemblMetazoa; AMIN006678-RA; AMIN006678-PA; AMIN006678.
DR   VEuPathDB; VectorBase:AMIN006678; -.
DR   OrthoDB; 5354081at2759; -.
DR   Proteomes; UP000075920; Unassembled WGS sequence.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00326; alpha_CA; 1.
DR   CDD; cd13394; Syo1_like; 1.
DR   Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR018338; Carbonic_anhydrase_a-class_CS.
DR   PANTHER; PTHR13347:SF1; HEAT REPEAT-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR13347; UNCHARACTERIZED; 1.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   SMART; SM00185; ARM; 3.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR   PROSITE; PS00162; ALPHA_CA_1; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   4: Predicted;
FT   DOMAIN          1..256
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000259|PROSITE:PS51144"
FT   REGION          615..637
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   911 AA;  101728 MW;  C37CFDDF9CBC0921 CRC64;
     MFPQARGQRQ SPVDIVTSKT QNSGDLQENP LRWTYVPENT RSLVNPGYCW RVDVNGKGSM
     LTGGPLQKEQ FILEQFHCHW GCSDSRGSEH TVDGESFAGE LHLVHWNQSK YKSFAEAAGH
     PDGLAVLGVF LKVGKPHPEL DIIARLLPFI THKGDRVTLN KPLDPARLLP EGKAYWTYLG
     SLTTPPCSES VTWILFKEPI EVSHEQLELF REMRCYDAAE ECPCDGTLNK QFEYGKVINN
     FRPPLELGNR QLPCRMGKAK KLKLHHNKPN PTGLMEVNEL IEQGLAESAK SGTPVEAIVE
     QLESAVVEEK ICGLQSLATI CQGEANIGEL VRNNVIRIAA SLLVDPDQSV RHATAGALRN
     LSVISVELCE FMVDQDVLTP LLALLVRFPS NGQWTPTFDK NMQNQMDEHS DTFLHAVNLL
     WNLCESTSDA LNAFNQSQLL ENFVSFLDYN VYGQEIAIAV AQCLLVVSED NASSWRVLAN
     HGAELLSLLT IQATDNATLM LRALSAGIIG NVPVLLSSHT SKVLISVSKT LEMNHRSALG
     NLTSMLPLEQ QKDLVDLEVT DDVVFDDETE AQSHQRRRKA DLPSEGELTV RDVGRLLQAQ
     RIAAEILTNI CSSEDDWQSE SNDNDNNAGS DAESVYDYDT NGLNESVENT DKISVEVLEA
     IKSLALVEKL WQKAQPVAEN VYQILVESEQ STLKKLDALR ISAMLCLHNL CNNISTDDLG
     GPTAVYNVWI DLGQQVFQGQ RNAKLLEAST SLMRAALEHL RKSPELFQQM TENDLQLMLN
     GVTGCEDIEI RANWLRMLGI LGCLLPESHV KVIIDFVLNT CANEADVWVL AEALDSMMDI
     FADNDWHSIM HELGMVTKCK QLDRIMREKL KRDKRQLGDR FPAVSTVRTN LGRFCKYLET
     ELKTFKPNME S
//