ID A0A182W8M1_9DIPT Unreviewed; 1347 AA.
AC A0A182W8M1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Raptor N-terminal CASPase-like domain-containing protein {ECO:0000259|SMART:SM01302};
OS Anopheles minimus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN006695-PA, ECO:0000313|Proteomes:UP000075920};
RN [1] {ECO:0000313|Proteomes:UP000075920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMIN006695-PA}
RP IDENTIFICATION.
RC STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN006695-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC {ECO:0000256|ARBA:ARBA00009257}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 112268.A0A182W8M1; -.
DR EnsemblMetazoa; AMIN006695-RA; AMIN006695-PA; AMIN006695.
DR VEuPathDB; VectorBase:AMIN006695; -.
DR OrthoDB; 103066at2759; -.
DR Proteomes; UP000075920; Unassembled WGS sequence.
DR GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR004083; Raptor.
DR InterPro; IPR029347; Raptor_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF14538; Raptor_N; 1.
DR PRINTS; PR01547; YEAST176DUF.
DR SMART; SM01302; Raptor_N; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 50..203
FT /note="Raptor N-terminal CASPase-like"
FT /evidence="ECO:0000259|SMART:SM01302"
FT REPEAT 1226..1267
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 210..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1036..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 784..800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..834
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..877
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1036..1064
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1347 AA; 149902 MW; ECD7DB086CDF9A68 CRC64;
MIETTEQSKD SNDTEDDDDA LLPVSFNCER HRGKIIGINC TTQCWRVRDR MKTVSVALVL
CLNIGVDPPD VVKIDKCARV ECWINPASYS PGKALEMISY QLQKQYERWQ PRARYRHSLD
PTMEDVKKLC TSLRRNAKEE RVLFHYNGHG VPRPTANGEI WVFNRTFTQY IPLSIYDLQT
WMGAPSIYVY DCSNAGIIVN SFNMFADQHE SELEQMRNRS GSTAGQPHTG TDLQTEDSRV
SPSPSAGVPG TTTYRNCIQL AACASDQLLP MNPNLPADLF TSCLTTPVKM GLRWFTLQST
SKLVPEVTEE LIEKIPGQLN DRRTMMGELN WIFTAITDTI AWNTLRPELF QKLFRQDLLV
ASLFRNFLLA ERILRAYDCT PISSPALPPS YRHPMWSAWD LALDQALAQL PDILEKGKPF
QHSPFFEEQL TAFQVWLEGS TEQRSPPEQL PIVLQVLLSQ VHRLRALELL GHFVDLGPWA
VNLALSVGIF PYVLKLLQSS AKELRPCLVF IWAKIVAVDG TCQIDLIREQ GHKYFLTALQ
DTHPGGQSFK GNHRTYAAFV LASIVHNFPN GQSSALQGQL VSICLDQLND DSNPLLRQWL
AICLGHLWQN YEQARWSGVR DNANEKLYPL LSDPYPEVRA AAVYALGTFI SSVKQRSDHA
NNIDRSTAMH LFATVSNDMS PLVRMELIAA LQWMVLFFET QFAGTFLQLD SPERSSNPMK
RVSSTSNIIG VGKASVMVGF YQKLWNGFIS LSKDPFPEVA TMAQKVVDYV RADSAKEVTV
CDKSSHHSGS AASISLPPSP NTRVGFLAGE SPPTHGGLHG SSDNGGSHQR LTSQQTPLAM
KKRIHAVNDS PSADYTDPQD KHTYTQNSSH SLQTSTTPLK PIVGTNFIEW SVSFFAQPSK
RMNETRAAGT DHNSYEFLSR KSRLLRNKEV RAEGRLQRKK AIFKRLDVQN WYCRTQHAPT
IIKLNPYDEQ VAFAYKDRVI VVNMNTDVTH TLTPSRQSIY DSFSSLASSN SSSFQSMPHH
GSQRLNNQSI SFLEQHHPSL SQSHQPLSFP HHQSKPSNES LPTHGIGSHA LAVTSLEFLN
AHDVGVIMAG YSDSTIRLWR PKDTSDENEL LSAWHGLMDF NTSSAAKVSC GESAPVAHGS
STAPGGLILA WHQSTQTIMA AGEAKYIRLW DAEREMRICD IPSGSDTAVL KMSCAPNGLL
AAGFYDGSVR IFDRRCPPTE TRCATIREHI NPVLAVCMRD DCESLVTAGV DAVVRLYDIR
KAYSSVQHWS AGTDVSAMAI HTSADILACA TTQITIYGLD GVILSTGRSN EGFMAPRKGV
ASCLSFHKFK LNLAAGYNDN TAAVLVP
//
