ID   A0A182WAH1_9DIPT        Unreviewed;       674 AA.
AC   A0A182WAH1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Major facilitator superfamily associated domain-containing protein {ECO:0000259|Pfam:PF12832};
OS   Anopheles minimus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN007349-PA, ECO:0000313|Proteomes:UP000075920};
RN   [1] {ECO:0000313|Proteomes:UP000075920}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMIN007349-PA}
RP   IDENTIFICATION.
RC   STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN007349-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC       {ECO:0000256|ARBA:ARBA00005241}.
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DR   AlphaFoldDB; A0A182WAH1; -.
DR   STRING; 112268.A0A182WAH1; -.
DR   EnsemblMetazoa; AMIN007349-RA; AMIN007349-PA; AMIN007349.
DR   VEuPathDB; VectorBase:AMIN007349; -.
DR   OrthoDB; 1365658at2759; -.
DR   Proteomes; UP000075920; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd17335; MFS_MFSD6; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 3.
DR   InterPro; IPR024989; MFS_assoc_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR16172:SF30; SUGAR BABY, ISOFORM C; 1.
DR   PANTHER; PTHR16172; UNCHARACTERIZED; 1.
DR   Pfam; PF12832; MFS_1_like; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        38..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        75..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        443..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        474..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        506..528
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        534..553
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..538
FT                   /note="Major facilitator superfamily associated"
FT                   /evidence="ECO:0000259|Pfam:PF12832"
FT   REGION          626..674
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   674 AA;  74377 MW;  F34C1B2A0E0329A6 CRC64;
     MVQLEINKKL LPMKAHYFLF NAGTAPVVPF MPTLVRQLGF STVIVGTIYT VLPIVGMLVK
     PLFGIIADRF QRQKLLFLIF QILTAVPFFL IMFIPAIPQD STVTFHCHNG AADLKYCPEN
     GTSIDSCLVE SITSNENNGS LLCDMECRTE PWMWDTVCKY WNVSTYCDEK NIPNDRILRL
     TGVVPNNHIN LVDECLFFML SEGKMDGNRV PLYCPANMTD FRTSCQVQCN NEQVMGAISH
     SKIADSDVTG LYQFWLLFLF LIISWAGMAV VVSVGDAICF EMLGDKPHLY GNQRLWGSIG
     WGTVSLFAGF LVDTLSEGKL AKDYTIVFYM TIVLIGFDML CSSKLQHTQT RLSTNILKDV
     GKIFVNFRIV VFFCWCVLIG FGTALIWNFL FWHLEDLASA QEGCGHSTWI KTLEGIIMSI
     QTFGGELPFF FLSGWILKKI GHIHAMSLVL LGFGVRFLLY SLLTDPWWVI PIEFMNGITF
     GLFYATMASY ASIVAPPGTE ATMQGLVGAV FEGVGVSLGS LLAGNLFHRI GGSSTFRAFG
     IAALVLFVLH VAVQKLTDRF GSQGKQQQKM DGLTGVKLKE NGTHGSGGLG GDGISNGQLP
     KINSILSEST VQEELHDGEE KEQLRYADGS HVDSKTASNG NVARHVPEMS SEKPSNGKTA
     VASTDGQLYE VPLN
//