ID A0A182WDX1_9DIPT Unreviewed; 560 AA.
AC A0A182WDX1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=E3 ubiquitin-protein ligase {ECO:0000313|EnsemblMetazoa:AMIN008564-PA};
OS Anopheles minimus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN008564-PA, ECO:0000313|Proteomes:UP000075920};
RN [1] {ECO:0000313|Proteomes:UP000075920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMIN008564-PA}
RP IDENTIFICATION.
RC STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN008564-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182WDX1; -.
DR STRING; 112268.A0A182WDX1; -.
DR EnsemblMetazoa; AMIN008564-RA; AMIN008564-PA; AMIN008564.
DR VEuPathDB; VectorBase:AMIN008564; -.
DR OrthoDB; 3430355at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000075920; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR004162; SINA-like_animal.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR013010; Znf_SIAH.
DR PANTHER; PTHR45877; E3 UBIQUITIN-PROTEIN LIGASE SIAH2; 1.
DR PANTHER; PTHR45877:SF2; E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED; 1.
DR Pfam; PF21361; Sina_ZnF; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS51081; ZF_SIAH; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00455};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00455};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00455}.
FT DOMAIN 111..174
FT /note="SIAH-type"
FT /evidence="ECO:0000259|PROSITE:PS51081"
FT REGION 322..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 62132 MW; 85499063E0E80EE7 CRC64;
KQPLKSVQAS VLTKSAAVLV KPSTETDSLV LVGRKWCGVW SPGSTCCMLK MESLRCKQCN
CFPNGEVYQC AANEHIYCAS CKESKDKVLC VCGAKLSDDT VPNPIEKMIH QAMCPCRYAP
NGCTWKFVQS EMDAHVAECR FRPYQCVAHS LNVIRCDWQG LQYEIEKHLT EGHKELGTMF
RFRETSSLVF KQEMSLGGMK LVDAFSKRFL FYNFSDIAHK KLSFLMIYFG RREEAKQYCY
ELELRAGPFP KKDSAEDGEP EGPVTFARTV KFVERCCSDS ENLAQMIAQE RCVSLTHRQV
QNYLHGEILH IAFKIRKVDG SREKKVSTGS VPAAEQSSQQ SGVSTKTKHR PPPFVFANKQ
KPAGGSGKRS ASSSSNASSC SGSSSSSSKS VKNATATNTS LPSRTPSTAS TVTACSARNS
TSADALTSSV NRCSLTSINR VSTPLTPFEK PEQCPLLTPS INKHDVPPSW SVSQTTMTGF
AYHTSTEYHR QAYGHVPYRS VHHYPPGECT TTASVCQRYT QPYKVQDDRP YLMKHPTNCL
YKPQAKWLAG NNTGKGDWST
//
