ID   A0A182WIA7_9DIPT        Unreviewed;      1619 AA.
AC   A0A182WIA7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Carboxylesterase type B domain-containing protein {ECO:0000259|Pfam:PF00135};
OS   Anopheles minimus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN010111-PA, ECO:0000313|Proteomes:UP000075920};
RN   [1] {ECO:0000313|Proteomes:UP000075920}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMIN010111-PA}
RP   IDENTIFICATION.
RC   STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN010111-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964}.
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DR   STRING; 112268.A0A182WIA7; -.
DR   EnsemblMetazoa; AMIN010111-RA; AMIN010111-PA; AMIN010111.
DR   VEuPathDB; VectorBase:AMIN010111; -.
DR   OrthoDB; 3035890at2759; -.
DR   Proteomes; UP000075920; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 3.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR   Pfam; PF00135; COesterase; 3.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 3.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 3.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT   DOMAIN          6..427
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   DOMAIN          497..993
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   DOMAIN          1055..1576
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          1536..1557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1619 AA;  179670 MW;  DB4602C6DE952770 CRC64;
     MDENCIVEVS SGLIKGLISR LPDGDGACYC FKGIPYAIPP VGSLRFRPPK RLTRHSEATL
     DCTTERAVSL ASNYLPPEPQ LASEDCLFLN VYTPINPNEL GQAGKPENLR PLPVMVWLHG
     GAFCTGSGDS SIYHPEWLVD ECVIVVTVNY RLGPAGFLCL PSMGIYGNMG LKDQRLALEW
     VQTNIGKFGG NAGNVTLFGE SAGAVSAHLH LLSEGSQHLF HKIICQSGVA TSSITFQTQP
     ESKTRRLAEF FGCSPDATDA DVLETLMMVE PELLAKSQKE ALTAHEKTLD SVYPFRPVLE
     RPDSIDPIIT ENVFVLLQRS NGPAKPMILG VTSEEAAYKI NTFRQYLHRY VEDKCRFIPD
     LLNVPRDERA QVAQSIIDFY CGPDGVCLER ELEMSRIFTD ILYLIPAVQA AELQLTHTQG
     DIFFYHFIPS KLPNAMVIRK LYVPPTVVQK NPLPPVVDPN FMPPATAYQP PAEDLPIVVE
     PESVANGGPL VFADNVEVEL VPGKIVGRRK ALPNGSEYYS YQGIPYAQPP VGDMRFKSPV
     PVEKFTEQPL DCGVERGTCL GVMTLPPGTV GVEDCLYLNV YTTSSPGETL GTLTPVMVWV
     HGGGYYTGSG NSNFFGPEFL LQHGVILVTM NYRLGPLGFL ALPSMGIHGN QGLKDQQLAL
     RWVHENITRF GGDPSNVTLF GESAGSASVN WHYLCPKSRQ YFHKAICQSG SVLCPWGLQR
     QPEGKARKLA AVLGYEGEDD AGVLDTLRNA SVEDLVSNSS KAFDDAEKCI YFVSPFIPSI
     EDASSEDAII LQSGEALLKQ PNVTSIPLIH GVNSAEGLVF YGLLQHLFDE VAGNLAMTLP
     LDLGIPRDFT SAVVEEVRQF YFQDKPIERG ELPRLLDLVA DVGFYFPVFV AAELHSRYQQ
     EAPLYFYRFS YETELNQLRK QFSVPDGTPG AAHADELSYL FSGSEFTVQV ENGSGPELAR
     TLLCRLWTNF AKFGCPTPDG DDVGFQWDPL PPTASGEPFV LRAVDLNDQV ETAEAVVQSD
     RINMVMRNVR KSNSAMANDG RASSVQDYDP AARIMVKVMQ GSIYGTKDRL PNGTPYYCFK
     GIPYAKSPVG KLRFASPVPI ERYSVSYLDC SRERSSCLGR DVITREITGS EDGLFLNVYT
     PALRREANAT DTLLPVIVFF HGGGMTGGNA DSSMYLPNYL VQEGTVVATV NYRLGVLGFL
     CLPQAGIEGN AGLKDQRLAL QWLNQNVKTF GGDPNNVTIL GASSGGSNVL MHCFSDHSRQ
     YFHKAIAQSA TIFADIIYQT EPEERARSLA RVFGYEGTSD DGVLSTLRDV PAQRLYEAQF
     LVLSAREREY EPIFHFPFTA VIEREQSADP VLLKTPMEYL RETDRVQVPL LCGYNDREGI
     LQLSDMITHL SVYNNRPERF ICRSFDVDYF SPAARTLGEE IKRHYFGEMP ISRTNLNQLV
     DLLTDRFVLG YYVLCKLWSE HQTKTPMYSY RFAYDGTLNK GKELLQFQQL PGACHIDEVY
     YLFSSSLLGT EIPPSDPAYR IRQLMVRMWT NFAKHSDPTP SSDETNVPCR WEPMRSVPGS
     NGEPTNYTIL SIGKELEMIT IPELKRMDKF LEMTKRCNGT IENFVIPRIG SQPESTKKC
//