ID   A0A182WLY9_9DIPT        Unreviewed;       783 AA.
AC   A0A182WLY9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Ionotropic glutamate receptor L-glutamate and glycine-binding domain-containing protein {ECO:0000259|Pfam:PF10613};
OS   Anopheles minimus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=112268 {ECO:0000313|EnsemblMetazoa:AMIN011418-PA, ECO:0000313|Proteomes:UP000075920};
RN   [1] {ECO:0000313|Proteomes:UP000075920}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MINIMUS1 {ECO:0000313|Proteomes:UP000075920};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles minimus MINIMUS1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AMIN011418-PA}
RP   IDENTIFICATION.
RC   STRAIN=MINIMUS1 {ECO:0000313|EnsemblMetazoa:AMIN011418-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A182WLY9; -.
DR   STRING; 112268.A0A182WLY9; -.
DR   EnsemblMetazoa; AMIN011418-RA; AMIN011418-PA; AMIN011418.
DR   VEuPathDB; VectorBase:AMIN011418; -.
DR   OrthoDB; 3685138at2759; -.
DR   Proteomes; UP000075920; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR   PANTHER; PTHR42643:SF24; IONOTROPIC RECEPTOR 31A, ISOFORM C-RELATED; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        425..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        521..544
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        714..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          302..400
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|Pfam:PF10613"
FT   REGION          180..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   783 AA;  87936 MW;  F04ACF6EF9D54DD4 CRC64;
     MHWTTGRLVR WYGVVVVVIL PVVVGLAYGT AVKSNDYSET VATFVLRFIR DHKGLKQGIV
     FGCDQKLLLI YKVLSQLATI GVRTRTVSID RVSPASPAGA DELVSSTLRR SLEFHQFVLL
     DMGCANAPDV LEQASKYELF NASFHWLIID KNYNSLVHGN KMMTAGNGAR FSTTEASVKN
     GVPSNRTVGP MPSFENGTID DRTRTASVDR RPIAKGDTFG LLATMNVSIN AEITVASPTD
     SSYRGFTLYD LWNPGFISGG KLKIEPLGRY TSADGRLLIA RRETTVVRRR NMGGLKLKIM
     TVVTQKPHRP FELYLTTPQN THLDSVHRYN YGLMSMLKDF YNFTFVNRRT KSWGYLRNGK
     FDGMIGALSR REVDLGGSPM FFRQERHRVV SYTTRTFVER PCFIFRHPPR NDAVKNPFLL
     PFEIIVWYLM VGCGTFLLAS CAGGTAAAAA AGSTAHNCHN KTVPANISST HRYQPGDGND
     GAKCNYKAEK VSKSILLFLG GVCQQGLSEI PHLSSGRCTS FFILLFGYLM YQYYSASIVG
     TLLMEQPKSI KTLRNLIDSR LTLGIEDIPY SRDYFVRTTD ADSLELYRTR IEYYEPAQGR
     NESHFLAAAD GLQLVRDGGY AFHVAISAAY RIIRLTFSER EICELSEIDM FPVWSQWMVA
     IVQKNSPYRD VITYGLRRLN EAGLMQRQRH VWQQPKPKCV RQIAPTDLIV SLDAVVSAFV
     LLCGGMVLSV CVLFVEVVRH RIERHRHAGC RPGPGRNRFV MMTKRHSLVT ADVGHGTELF
     YVE
//