ID A0A182WT60_ANOQN Unreviewed; 797 AA.
AC A0A182WT60;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=E3 ubiquitin-protein ligase RNF10 {ECO:0000256|ARBA:ARBA00035131};
DE AltName: Full=RING finger protein 10 {ECO:0000256|ARBA:ARBA00035390};
OS Anopheles quadriannulatus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34691 {ECO:0000313|EnsemblMetazoa:AQUA000714-PA, ECO:0000313|Proteomes:UP000076407};
RN [1] {ECO:0000313|Proteomes:UP000076407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SANGQUA {ECO:0000313|Proteomes:UP000076407};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles quadriannulatus QUAD4_A.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AQUA000714-PA}
RP IDENTIFICATION.
RC STRAIN=SANGQUA {ECO:0000313|EnsemblMetazoa:AQUA000714-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RNF10 family.
CC {ECO:0000256|ARBA:ARBA00008117}.
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DR AlphaFoldDB; A0A182WT60; -.
DR STRING; 34691.A0A182WT60; -.
DR EnsemblMetazoa; AQUA000714-RA; AQUA000714-PA; AQUA000714.
DR VEuPathDB; VectorBase:AQUA000714; -.
DR Proteomes; UP000076407; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd16536; RING-HC_RNF10; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039739; MAG2/RNF10.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12983; RING FINGER 10 FAMILY MEMBER; 1.
DR PANTHER; PTHR12983:SF9; RING FINGER PROTEIN 10; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 227..268
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 636..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 343..397
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 797 AA; 86971 MW; 1AD9213158C81F68 CRC64;
MEKNRYTSQN LSKGQISETK KGQDVSVKWP RQSKRRGEQS DSANNHRNGA STGKVPNSNK
NRNQSNYNYD ARQRSQRVGR PADQLALSAD GGDIGTGALA EEQPAASGTA GLVPPARPNT
TPTGARGELH SVFTPGSKKQ SLNHLLNYHY APRERDQPVR FTRTGNLRKL TNQSHGSYNK
EQFLQANCQF VVRAGEDYEP LLSAPDQLVD WGKVEQIHVL SSEEPQCPIC LYPPVAAKMT
KCGHVYCWPC ILHYLALSDK SWRKCPICYE AIHLPDLRSA VSKPFHAYGM GEYVTLQLMR
REKGTMKVVE VNDELPTVAA NHRVLIPHFD ATAGNSILTK LLLTDTEQML KIMEREQTEL
QNQLVTDGAD EPENMFVQQA LELLAEKRTN LKAAKAIVFP VAIEKIVRGT SVSSSGSEEV
GEQQPQETGE DKEGSAEGSA SAVPGSGEGS PDFVIDEESN FTVGDIDIVP TAQCAGEHFY
FYQSVDGQPL FLHSINSRML QTMYGSLDRS PHRITGRVVQ KDSCSMDENL RRRLKYLEHL
PVCTQFDVVE LDFGPASGGL VSEEVLGLFH DELSMRQRTR QKRAKAEQKR EKQIFEFNER
QLGKAMARSA RISIDSTKQF PSCGFSDSYL DDPSPFGSSP VASDISSSPG SSGSAMSSWS
KMVSTQPSSG QRWPTLGGGG GGATSSNAPP PKLVQVTGSR MTASTSSAYR TGWRNPAASS
DIEEDETDEE LIAARAPRFN NNLGRAIEAA LEKKISHPNQ SNAGAAAAAA GASGSGAAGK
RKKNKKTLLF ASGMNLN
//
