ID   A0A182WXI7_ANOQN        Unreviewed;       942 AA.
AC   A0A182WXI7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
OS   Anopheles quadriannulatus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34691 {ECO:0000313|EnsemblMetazoa:AQUA002247-PA, ECO:0000313|Proteomes:UP000076407};
RN   [1] {ECO:0000313|Proteomes:UP000076407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SANGQUA {ECO:0000313|Proteomes:UP000076407};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles quadriannulatus QUAD4_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AQUA002247-PA}
RP   IDENTIFICATION.
RC   STRAIN=SANGQUA {ECO:0000313|EnsemblMetazoa:AQUA002247-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR   AlphaFoldDB; A0A182WXI7; -.
DR   STRING; 34691.A0A182WXI7; -.
DR   EnsemblMetazoa; AQUA002247-RA; AQUA002247-PA; AQUA002247.
DR   VEuPathDB; VectorBase:AQUA002247; -.
DR   Proteomes; UP000076407; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00054; EGF_CA; 5.
DR   Gene3D; 2.10.25.10; Laminin; 13.
DR   InterPro; IPR026823; cEGF.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR   InterPro; IPR018097; EGF_Ca-bd_CS.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24034:SF198; RE68558P; 1.
DR   Pfam; PF12662; cEGF; 1.
DR   Pfam; PF07645; EGF_CA; 11.
DR   SMART; SM00181; EGF; 11.
DR   SMART; SM00179; EGF_CA; 13.
DR   SUPFAM; SSF57196; EGF/Laminin; 2.
DR   SUPFAM; SSF57184; Growth factor receptor domain; 4.
DR   PROSITE; PS00010; ASX_HYDROXYL; 5.
DR   PROSITE; PS01186; EGF_2; 4.
DR   PROSITE; PS50026; EGF_3; 4.
DR   PROSITE; PS01187; EGF_CA; 4.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW   ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT   DOMAIN          371..409
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          597..638
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          639..682
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          724..766
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
SQ   SEQUENCE   942 AA;  104081 MW;  24614ED66EFA7CC4 CRC64;
     MAGAIAIEQI LSLCCQEGEE WGLQSRTCSS FNKSLELVPA GLHGLCLSTI EICCSKQHKI
     YQCTAGQIAA RQGLSCSLKG DHSGSEFYTD CCEACKIGLV VGSSANKCSV EPFAFGSPWD
     EIYDACCNDI KKEGEIILLS GNDEQSLCEQ FPSICSQVCE NVEGGSYVCK CHPGYELLDD
     RKTCALVSDE DNETVERKGC DAGFKHNKRT DKCEDVNECE TGEATCNPDS QVCRNTRGSF
     LCVDVVLPDI ACDPGYTPKN GKCEDVNECL EQLDACDRER QHCLNGRGNY SCLPKAVTMC
     QPGFAYNVSL GVCEDVNECE EDGACDEGYR CVNIEGSYEC IAVVKNYPTP ARKKVETCTP
     GFRRHNDQCV DIDECAADRN ACDSNQVCTN EIGGFRCDCK IGFNLDTVTN ACVDINECQV
     NAHECLETQR CDNTIGSYTC IRLQSCGTGY TLNAETGHCD DDDECALGRH NCRPPFECFN
     TKGSFRCRQL SRYHTLTSTS TSTTTSTTTV RPSYNPAGYG HYPASRYSSY QPQLPPCGIG
     FERNSAGACV DIDECARGAS CHRHQQCINT NGSYRCRDLL TCPVGYRVND DITECLDIDE
     CATGEALCGP DQTCKNKKGG YVCVCPPGHM IGRNKRCEDI DECAMHGSKV CQQNSNCVNT
     IGSYRCDCKE GFKNGPNEMI CTDVDECKEI PGLCHQRCLN YWGSYRCGCH PGYRISYNNR
     TCDDVDECEE YKSANLCVGI CENTPGSYSC RCPHGYKLGA DGRSCIDIDE CETGDVCRGR
     QDICTNIGGS YRCTTIDCPY GYKHDPDRRN RCERSNKYCN TGDMECLRRP HSYSYNFLTI
     VSNILIPPEG RGLFTLTGPS HFQMIDFDLK LVSVDAAPHV KPVDIHYFGL EKRTNDAQLN
     LKKSIEGPQD IELELSMSVF HNGELYGTNV AKLFLMISAY EY
//