ID   A0A182XA26_ANOQN        Unreviewed;       780 AA.
AC   A0A182XA26;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2023, sequence version 2.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Nose resistant-to-fluoxetine protein N-terminal domain-containing protein {ECO:0000259|SMART:SM00703};
OS   Anopheles quadriannulatus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34691 {ECO:0000313|EnsemblMetazoa:AQUA006665-PA, ECO:0000313|Proteomes:UP000076407};
RN   [1] {ECO:0000313|Proteomes:UP000076407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SANGQUA {ECO:0000313|Proteomes:UP000076407};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles quadriannulatus QUAD4_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AQUA006665-PA}
RP   IDENTIFICATION.
RC   STRAIN=SANGQUA {ECO:0000313|EnsemblMetazoa:AQUA006665-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A182XA26; -.
DR   EnsemblMetazoa; AQUA006665-RA; AQUA006665-PA; AQUA006665.
DR   VEuPathDB; VectorBase:AQUA006665; -.
DR   Proteomes; UP000076407; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   InterPro; IPR002656; Acyl_transf_3_dom.
DR   InterPro; IPR006621; Nose-resist-to-fluoxetine_N.
DR   PANTHER; PTHR11161; O-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR11161:SF0; O-ACYLTRANSFERASE LIKE PROTEIN; 1.
DR   Pfam; PF01757; Acyl_transf_3; 1.
DR   Pfam; PF20146; NRF; 1.
DR   SMART; SM00703; NRF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..780
FT                   /note="Nose resistant-to-fluoxetine protein N-terminal
FT                   domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5037595966"
FT   TRANSMEM        243..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        417..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        544..560
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        567..585
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        605..623
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        635..655
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        675..694
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        706..724
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        744..769
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          79..229
FT                   /note="Nose resistant-to-fluoxetine protein N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00703"
SQ   SEQUENCE   780 AA;  88155 MW;  AFE71F3F47B6C5E5 CRC64;
     MKRNRIWSGW SISVFMLVAL LHCSATGGQE VNVSLVQPEG TNQSINFSFD RLILLEEKLT
     VFDIKRIASG WSTLRPRLSG TCGDQMTQYL LGLQEEKLWA LKMDDSSGKY TKGFFWGNNY
     WTGSMDQCSY IHQNDSDSDP APKKKGRNTD ITYINGNFLG SSEMEHQNPP FVPGFYMAKI
     LINGTESFNA IRTVVVGLCL PSGCSIADVE TLLKLDIDRR HVDQELVGVR SPTLNNFSLW
     DDFTFRILFV FSVIVVILLI SGTGYDLVLR RRYKAKMRIK SYCKELTGDM TNGLGCTTYD
     LTHREPEENG KGNCTVIRVP TSVNNNNSDE NLAVELTATE ETKLSLWAEL LLSFSVVTNF
     KAICDKNVGN DTIPSIHGLR AISMAWVILG HTMIVVFKYS DNMELRKVVE KEFLFQIVLN
     GAYSVDTFFF ISGFLVSFIY FRTNAKGKLE KLTKGVSEFT AGTFHFFGLV GYRFVRLTAP
     YLYVLGVVEV VMRYLEQNSV FEPPTQDHIN CPKYWWRNIL YINTLFPVEQ MCMLWSWYLA
     DDTQFYIIGA LILIIAVRHF KFAATMMSVF MVSAWATTAY IAFSNNHMPD ADDPFALFDK
     IYDKPWTRLG PYLVGMSVGW ILFKTNCKIK MSLLTVISGW VTSTMMMLYL LFGLYNTTLT
     QTAAAAYSSL SHTGWAIGCG WVIVACSSGY GGWVNKLLST PILYPFSRVT YCAYLVHPII
     NRIFALESDS PIHMTPNALA TVYLGQVVSS YVLAFIISLS FEAPVVTMLK ILSPNRKKRI
//