ID   A0A182XLL2_ANOQN        Unreviewed;       506 AA.
AC   A0A182XLL2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 5 {ECO:0000256|ARBA:ARBA00016266};
OS   Anopheles quadriannulatus (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=34691 {ECO:0000313|EnsemblMetazoa:AQUA010757-PA, ECO:0000313|Proteomes:UP000076407};
RN   [1] {ECO:0000313|Proteomes:UP000076407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SANGQUA {ECO:0000313|Proteomes:UP000076407};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles quadriannulatus QUAD4_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AQUA010757-PA}
RP   IDENTIFICATION.
RC   STRAIN=SANGQUA {ECO:0000313|EnsemblMetazoa:AQUA010757-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
CC       {ECO:0000256|ARBA:ARBA00009710}.
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DR   AlphaFoldDB; A0A182XLL2; -.
DR   STRING; 34691.A0A182XLL2; -.
DR   EnsemblMetazoa; AQUA010757-RA; AQUA010757-PA; AQUA010757.
DR   VEuPathDB; VectorBase:AQUA010757; -.
DR   Proteomes; UP000076407; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005849; C:mRNA cleavage factor complex; IEA:InterPro.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:InterPro.
DR   Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR   InterPro; IPR016706; Cleav_polyA_spec_factor_su5.
DR   InterPro; IPR027012; Enkurin_dom.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   PANTHER; PTHR13047:SF0; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5; 1.
DR   PANTHER; PTHR13047; PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT; 1.
DR   Pfam; PF13864; Enkurin; 1.
DR   Pfam; PF13869; NUDIX_2; 1.
DR   SUPFAM; SSF55811; Nudix; 1.
DR   PROSITE; PS51665; ENKURIN; 1.
DR   PROSITE; PS51462; NUDIX; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          80..205
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS51462"
FT   DOMAIN          404..498
FT                   /note="Enkurin"
FT                   /evidence="ECO:0000259|PROSITE:PS51665"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   506 AA;  58377 MW;  92C38DFF4610C275 CRC64;
     MTSQAVNKTG SGWPRRNSHG TGLTEMNKLQ TNQSMTLNRT INLYPLTNYT FGTKEPLFEK
     DPSVPARFQR MRDEFDKIGM RRSVEGVLLV HEHGLPHVLL LQLGTTFFKL PGGELSAGED
     EVDGLKRLLT ETLGRQDGVK QDWIVEDTIG NWWRPNFEPP QYPYIPPHIT KPKEHKRLFL
     VQLHEKALFA VPKNYKLVAA PLFELYDNSQ GYGPIISSLP QALCRFNFIY IPACSCSSSA
     YHPNMSIVNI YIHDENIYNV EKKPPEKPPK PPLYHSRFEH QVRQETKSCK DAHRTMGFSK
     IPLPGPADFL RKNCGPRHRA TKSAPVRLCT GHKPPIPKPH EPSPCQVLKV VDFRKENIKK
     VVAANPKKPR PRYADTRKGD FHDLEKSGLM PIYMCQPKFG KVPQYLTRRK KDLAAQKDRL
     IEDRAQQQPR CSYILQEERV ELLKGLKKNW EKLQQEYQSL PLLTDTVPKM IRKAKLENNL
     KQLEKDILTI ENNPYIYLYD DDQKDA
//