ID A0A182XQC2_ANOQN Unreviewed; 312 AA.
AC A0A182XQC2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Malectin domain-containing protein {ECO:0000259|Pfam:PF11721};
OS Anopheles quadriannulatus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=34691 {ECO:0000313|EnsemblMetazoa:AQUA014067-PA, ECO:0000313|Proteomes:UP000076407};
RN [1] {ECO:0000313|Proteomes:UP000076407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SANGQUA {ECO:0000313|Proteomes:UP000076407};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles quadriannulatus QUAD4_A.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AQUA014067-PA}
RP IDENTIFICATION.
RC STRAIN=SANGQUA {ECO:0000313|EnsemblMetazoa:AQUA014067-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}.
CC -!- SIMILARITY: Belongs to the malectin family.
CC {ECO:0000256|ARBA:ARBA00009141}.
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DR AlphaFoldDB; A0A182XQC2; -.
DR STRING; 34691.A0A182XQC2; -.
DR EnsemblMetazoa; AQUA014067-RA; AQUA014067-PA; AQUA014067.
DR VEuPathDB; VectorBase:AQUA014067; -.
DR Proteomes; UP000076407; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR039155; MLEC.
DR PANTHER; PTHR13460:SF0; MALECTIN; 1.
DR PANTHER; PTHR13460; UNCHARACTERIZED; 1.
DR Pfam; PF11721; Malectin; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..312
FT /note="Malectin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008143313"
FT TRANSMEM 291..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..195
FT /note="Malectin"
FT /evidence="ECO:0000259|Pfam:PF11721"
FT REGION 262..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 34937 MW; 103EFA0F8C789C61 CRC64;
MFKHQLGRIR IFSILALLFY AVKASTGSSA HNVIYAINAG GDEVTDSNGI QYSRDPLKGK
VGTESDYGRQ LLSINRVSKQ DEILYQTERY HHDTFAYDLP VSGDGQYVLI LKFCEVYFNG
PNMKVFDVLL DHHLIISDLD IYSLVGKGTA HDELVFFSVS RGRLYLKDKQ SEIRGSKLKL
EFVKGYKDNP KINAILLIKD YDASLLPRLP PLANQHQTAG ATNMDNSIEQ LHPHSDFLSD
DDGHMLEGGE DNIMDDFFST SSEDTAKTSS KQRKTSGPKQ PNPYSLDDSS IMLPVFIAIG
AFIPLLFCLC RL
//
