ID   A0A182XYS7_ANOST        Unreviewed;       152 AA.
AC   A0A182XYS7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   13-SEP-2023, entry version 29.
DE   SubName: Full=ML domain-containing protein {ECO:0000313|EnsemblMetazoa:ASTEI01363-PA};
OS   Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI01363-PA, ECO:0000313|Proteomes:UP000076408};
RN   [1] {ECO:0000313|Proteomes:UP000076408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX   PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA   Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA   Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA   Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA   George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA   Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA   Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA   Sharakhov I.V., Tu Z.;
RT   "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT   stephensi.";
RL   Genome Biol. 15:459-459(2014).
RN   [2] {ECO:0000313|EnsemblMetazoa:ASTEI01363-PA}
RP   IDENTIFICATION.
RC   STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI01363-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NPC2 family.
CC       {ECO:0000256|ARBA:ARBA00006370}.
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DR   AlphaFoldDB; A0A182XYS7; -.
DR   STRING; 30069.A0A182XYS7; -.
DR   EnsemblMetazoa; ASTEI01363-RA; ASTEI01363-PA; ASTEI01363.
DR   VEuPathDB; VectorBase:ASTE005898; -.
DR   VEuPathDB; VectorBase:ASTEI01363; -.
DR   VEuPathDB; VectorBase:ASTEI20_039804; -.
DR   OMA; QERTHIC; -.
DR   Proteomes; UP000076408; Unassembled WGS sequence.
DR   GO; GO:0032934; F:sterol binding; IEA:InterPro.
DR   GO; GO:0015918; P:sterol transport; IEA:InterPro.
DR   Gene3D; 2.60.40.770; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR003172; ML_dom.
DR   InterPro; IPR039670; NPC2-like.
DR   PANTHER; PTHR11306; NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED; 1.
DR   PANTHER; PTHR11306:SF36; NIEMANN-PICK TYPE C-2C-RELATED; 1.
DR   Pfam; PF02221; E1_DerP2_DerF2; 1.
DR   SMART; SM00737; ML; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000076408}.
FT   DOMAIN          23..148
FT                   /note="MD-2-related lipid-recognition"
FT                   /evidence="ECO:0000259|SMART:SM00737"
SQ   SEQUENCE   152 AA;  16862 MW;  0F81C649963B7C48 CRC64;
     MRNLVLFFVT LLVCGGCAER LQTRSCSNGR PHPSYVVISG CSQMPCLLPR NTNVTVTMVY
     EAPYAAESLT FKQIVTALGV TIPVELSPER ANACDRMLGT SCPLRPHEVV ITTHTIIVMP
     IYPVVTMFVE FSAVDEQERT HICFIFDVQI VP
//