ID A0A182XYZ7_ANOST Unreviewed; 1835 AA.
AC A0A182XYZ7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ASTEI01433-PA};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI01433-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI01433-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI01433-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 30069.A0A182XYZ7; -.
DR EnsemblMetazoa; ASTEI01433-RA; ASTEI01433-PA; ASTEI01433.
DR VEuPathDB; VectorBase:ASTE002372; -.
DR VEuPathDB; VectorBase:ASTE003916; -.
DR VEuPathDB; VectorBase:ASTEI01433; -.
DR VEuPathDB; VectorBase:ASTEI20_039751; -.
DR OMA; QRAMDIE; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF71; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000076408}.
FT REGION 531..553
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 59..66
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1835 AA; 211697 MW; 7606341D9AF439F8 CRC64;
LFCVVVNPYK KLPIYTEKIM EKYKGIKRHE VPPHVFAITD TAYRSMLQDR EDQSILCTGE
SGAGKTENTK KVIQYLAYVA ASKPKGSVAG ELEQQLLQAN PILEAFGNAK TVKNDNSSRF
GKFIRINFDA SGYISGANIE TYLLEKSRAI RQAKDERTFH IFYQLLAGAS PEQRERFILD
DVKTYPFLSN GGLPVPGVDD YAEFQATVKS MNIMGMTSED FNSIFRIVSA VLLFGSMTFK
QERNSDQATL PDNTVAQKIA HLLGLSVTDM TKAFLTPRIK VGRDFVTKAQ TREQVEFAVE
AIAKACYEKM FKWLVNRINR SLDRTKRQGA SFIGILDMAG FEIFELNSFE QLCINYTNEK
LQQLFNHTMF ILEQEEYQRE GIEWKFIDFG LDLQPTIDLI DKPGGIMALL DEECWFPKAT
DKSFVEKLAA AHSMHPKFMK TDFRGVADFA VVHYAGKVDY SATKWLMKNM DPLNENVVSL
LQASQDPFVV QIWKDAEIVG MAQQALTDTQ FGARTRKGMF RTVSHLYKEQ LAKLMDTLRN
TNPNFVRCII PNHEKRAGKI DAPLVLDQLR CNGVLEGIRI CRQGFPNRIP FQEFRQRYEL
LTPNVIPKGF MDGKRACEQM IKSLELDSNL YRIGQSKIFF RAGVLAHLEE ERDYKITDLI
VNFQAFCRGF LARRNYQKRL QQLNAIRIIQ RNCAAYLKLR NWQWWRLYTK VKPLLEVTKQ
EEKLVQKEDE LRQIRDKLEN LSKNSQEYEK KYQQAVEEKT HLAEQLQAEI ELCAEAEEGR
ARLVARKQEL EELMQDLESR IEEEEERVNA LTSEKKKLQI NIQDLEEQLE EEEAARQKLQ
LEKVQLDAKL KKMEEDVALI EDQNHKLVKE KKLLEERAND LSQTLAEEEE KAKHLAKLKV
KHESTIAELE ERLLKDHQQR QEADRSKRKI ETEVADLKEQ INERRMQIEE MQQQLVKREE
ELAQTLVRID EESAAKAAAQ KTQRELESQL AEIQEDLEAE KLARSKAEKQ KRDLNEELEA
LKNELLDSLD TTAAQQELRS KREQEVATLK KTLEDESANH ESTLMDMRHK HAQEISSINE
QLENLKKMKG GLEKSKQQLE AENADLATEL RNVNQSRQEN DRRRKQAETQ IAELQVKLAE
VDRVRVELQD KVTKLQQETE NITQQLDEAE LKASAAIKSA GNLESQLTEA QQLLEEETRQ
KLALSSKLRQ IESEKEALQE QLEEDEEAKT NYEKKLAELN FTIQELKKRS EEDSDIAKEL
EESKKKMNKD IETLQRQIQE LQAANDRLDK SKKKIQSELE DATIELETQR TKVLELEKKQ
KNFDKVLAEE KAIGEQVAQE RDAAEREARE KETKVLSLSR ELDEAFEKID ELETKRKGLQ
NELDELANTQ GTADKNVHEL EKAKRALESQ LAELKAQNEE LEDDLQLTED AKLRLEVNMQ
ALRAQFERDI QAKEEQSEEK RRGLVKALRD LEAELDEERK QRAAAVAAKK KLEGDIKDME
ATLEMNNKVK EDALKQAKKL QAQIKDAIRD AEEAKAAKEE LAAISKESER KVKTLEADVM
QLSEDLSSSE RARRAAEGER DELLEEINSN SSKGSLMIDE KRRLEARIAA LEEELEEEQS
NLELMVDRNR KAQLTIEQLT TELATEKSNA QNNETLKCGL ERLNKELKAK LSEQETALRT
KLKAATAASE AKNMNLEKQL ENETKERLAV QKANRKLEKR IKELTMNIED ERRHADQFKE
QIEKANNRMK TLKRNLDEAE EEIQKEKTLK RKAQRECEDM LESHEALSRE VNALKSKLRR
GGAMGSLSSS RLTPKRENDS ISVQDESLDG EDNSN
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