ID A0A182Y0W5_ANOST Unreviewed; 1244 AA.
AC A0A182Y0W5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=VWFA domain-containing protein {ECO:0000313|EnsemblMetazoa:ASTEI02101-PA};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI02101-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI02101-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI02101-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182Y0W5; -.
DR STRING; 30069.A0A182Y0W5; -.
DR EnsemblMetazoa; ASTEI02101-RA; ASTEI02101-PA; ASTEI02101.
DR VEuPathDB; VectorBase:ASTE010302; -.
DR VEuPathDB; VectorBase:ASTEI02101; -.
DR VEuPathDB; VectorBase:ASTEI20_033500; -.
DR OMA; EIHRIHA; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR CDD; cd01463; vWA_VGCC_like; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013680; VDCC_a2/dsu.
DR InterPro; IPR013608; VWA_N.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10166:SF63; STRAIGHTJACKET, ISOFORM C; 1.
DR PANTHER; PTHR10166; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED; 1.
DR Pfam; PF08473; VGCC_alpha2; 1.
DR Pfam; PF13519; VWA_2; 1.
DR Pfam; PF08399; VWA_N; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022673};
KW Calcium channel {ECO:0000256|ARBA:ARBA00022673};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022673};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022882};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
SQ SEQUENCE 1244 AA; 142681 MW; 02873822D7931FB3 CRC64;
MLYIGGRSSC GILAFTFLLF FAISITRSAD EPTTTIKYNV VQAWAAKLGG ELWHLGDFIT
RRKEVEESFK QAQVVSKNGQ KIVEEMAKDL KYMMDAKVSA VKRIMDTAEN TAISFDEEPV
NQSFQYYNAK QMIEPGEIIT TPIPMIDEDP ADITTPIPPK EIVLTKKRHF FNEAVNTTVS
SVHVPTNVYD RATEVIKAIK WSEALDSIFY NNYIGDPTLT WQYFGSSSGF LRQFPATKWE
QDPVDLYDCR LRSWYIEAAN SPKDMLILVD SSGSMTGQRK DIAKHVVSNI LDTLGPNDYV
NIFTFSEEVA EVVPCFRDTL VQANMGNIRE LKLGMDNIET NEIANVSAAL TRAFELLEQF
RETRNGARCN QAIMLVSDGV PYSFDEVFEQ FNWKELPFIP VRVFTYLIGR EVADVKEIKE
MACRNQGYYV HLSTMAEVRE EVLNYIPVIA RPLVLNKREH PVVWSEIYAD VEDPKMTDWL
WEIKERAEQK ERFIDYRKNR VLFYSPEEQH RRMIMKQRMN QDPYSNNQKY NFMTTVSVPV
FDRRENATRV ANILGVAGAD VPIAEIKKYL KPHLLGVNGY AFIVTNNGYI LTHPDFRPVF
QDILKPAYNT VDMIEVELTD DDQGPRDFNN MLLNMRESII NQSTGAKWIR VKYHFDEMKR
VSRTKRQYYW TPIKNTPFTL VVTYPETYGV NRLQIRTEDE IHRIHAKGSN VASFFSGNNW
KIHPDWVYCK YLNEHPNETF GTPELELKHF LERMKLGGWK WPSNRTPPPP EHAMFCDRGL
MQALVYDAKV TEWFSKNVSG SGGNKDEKGN EFKQRFGITV SFLATHSGLT RWQEYATGAD
ESKQAEPDFS ETHNRAIDEV WYKRAVELYY SNRNRKGADG ENGKDDSDRN SFVYSVPFDA
GNRNDTLVTA SHAIFHTDGT REAPVAVVGF QFHHSALYTL FKNITSQCGH GDPRCEKTCF
TGDYQCYVID NNGFVVISEQ LQETGAFFGE VKPAFMQRLL DDSIFRNVTV YDYQAVCFMP
KGSINLGTVL QTPLRLLWWI LTNTLSYLVW VVMQLLLSLA QAYDEIYDTG AYDVVPELGD
LDDPTLNRYK EPEFNKVLIN RTRPEPCDHV ITLYELNMDV DPSVYTKEAH QCERPYVVLP
IPSSNLLLLV LDTLCPLPTH VPQLSTWPVE HDYNASLACH KARSDPLPRR RPLTCINKHA
NESVIELCGD GSIPRYNVAL LLALLVFGQC IVQRCTAGGI FAYL
//
