ID A0A182Y0Z6_ANOST Unreviewed; 3476 AA.
AC A0A182Y0Z6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ASTEI02132-PA};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI02132-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI02132-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI02132-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 30069.A0A182Y0Z6; -.
DR EnsemblMetazoa; ASTEI02132-RA; ASTEI02132-PA; ASTEI02132.
DR VEuPathDB; VectorBase:ASTE010270; -.
DR VEuPathDB; VectorBase:ASTEI02132; -.
DR VEuPathDB; VectorBase:ASTEI20_034487; -.
DR OMA; RGFTVRW; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 25.
DR CDD; cd00054; EGF_CA; 6.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 25.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24251:SF37; CUB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR Pfam; PF00431; CUB; 25.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF12661; hEGF; 2.
DR SMART; SM00042; CUB; 25.
DR SMART; SM00181; EGF; 8.
DR SMART; SM00179; EGF_CA; 7.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 25.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS01180; CUB; 24.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DISULFID 131..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 174..183
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 391..400
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 432..441
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 569..596
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
SQ SEQUENCE 3476 AA; 384983 MW; 865A4078A5D40090 CRC64;
MKGSGHLNIG GLSVEQVLRT LSKMMIEGRS SPDSQTFLPG GSVADQVQLL ATYVSGPFGL
IKRVETLEQE SSTRNTTQMH PRIGALVRRV RNVETKLAAL LTTLQANRCA SGPCQNGGTC
IAQYDSFMCL CPSNWEGQTC TTDVNECSLF AGTDLGCQNG ATCKNVHGGY NCMCADGWRG
IHCNTRSQDC STAGADLCGH GTCVQAKDGY RCICDQGWKT NGLTPACSQD VDECSESKPH
CSKDPEVSCI NLPGSFVCGP CPAGYTGNGF YCVDIDECET NNGGCSTSPS VPCINTRGSY
RCGNCPAGYT GDGRTCLAQG NRCTQGLCHP MARCVDYGSA VPNCICLPGY TGSGFGPNGC
YRSSMNPCSS SPCRNGGTCV KIDAQNYSCT CPPDTNPPNC MRTTSPCDSN PCQNGATCVA
GWGNSGRFGC RCAPGYTGLR CQTLTRTCGG IRYQLNGTLR YPEFNGTYNH NARCAWLIKT
NDTQVLDVTF TQFDLENPVS TGECKYDWLQ IHDGRTSAAQ IIGRFCGSEL PRGGNFQSTH
NMLYLWFRSD NSTAHDGFEL QWKSVAPVCG GTIAVTSHGI ITSPGTPGNY PPNRDCKWFL
QAPQGRRIQF TFFTMMIEVH ENCNFDFVQI SEGVTDEGTV LAKYCNTTHP PPLITPSHEA
TVYFHSDESG NDAGFQISYA VVEGVPGCGG TYTQREGAIS SPLSQTDNVY PNNLNCEYLI
KLPIGSRVEI RFSKFHLEQS EGCKFDYLEI FDGSSTEDAS LGKFCGDRMP PTFTSTGHAL
LLKFHTDWSA PNPGFSLVYK IKCGGTFTDP GVEIMSPSYP QMYQADQLCD YVIQAPLGKA
ISFDFQDFDI EKNSFPRCEL DYVELYDGLL PTNETLLGRY CSTKAPPTTV SSKNVMLVRF
VSDGSVAGRG FKGNFSFFDV SCGGVLMRED TIIRSPMIAE TGKYQHDAQC EWIIVAPEGH
AIQLMWNSFE LEVSGRCVYD YVQVFDNSSI ANSLIGRYCG TDKPPAITST GNMVTIRFVT
DSSSSKDGFS LAFNFIDVEK SCGGNYFATS GIIRSPGWPK NYLSNKVCEW VITVPMGQQI
TLLVHSFRME KHKTCRFDGL TIRNGGTQHS PLIGDFCGED DFNGTISFSH QLYLRFYSDS
SRNYAGFMIE WDSATTGCGG VLTSPRGSII SPNYPLPYGQ NALCIWRISM SEGSAIHIVF
TDLDMENHKD CQYDYLDIYD GGDMGARKLG RFCSAETDPI VLDTESNHAL IRMRTDESNQ
RRGFQLKYNI LCRRNITGFG GIIESPNFPS EYAASMDCRW TIRVPPGNRI NLEFSHFDFE
SINQQGLDNA THQRCPFDYV ELQEMGSGDL PVVRRYCANK PAPFVSVGRS IDLIFHTDAS
GEQMGFRAEW SINGCGGLLT KPYGTFSSPN YPNQYPKETE CHWTIRAPPG KRIDLMVEDF
HMETNDQCRF DGLQIANDAN FTHQVTKLCH EQQEPVHLVS GGTELFVKFY SDSTFTYKGF
RAVYKTIELQ CGGKITLHQG FISSPNYPLN YPANASCSWL IKTDLSHTLQ LSIKSLAIER
SDNCTNDSLQ VYDSNTAELD RLLLTACGSE SNVSTVSSTG HEMLVTFQSN HIIEAKGFQA
EFKTNCGSRI KVKRPGNILL NKAHKMSSDN CTWVLIAPEP TERITITIAH MSVMDVERDC
FASLTVYEGD GTDGPVRFEG CGHKIPPAIV SRGNALTVLI SSEDVLLSKI DNLLTALMGE
FSSPNYPDTY PLNVECVWKL SASPGNKMTL SFKELDIDSS EDCNGDYLEV RERDENGPLL
GDFCGNQLPS NLSEASSFWV KFRSNEVGVG KGFLAEYSYD TLSEITGASG TVTSPMYPRS
YARADNIGWR ITVDIGSVIA LNFNRFAIDR HTEDPEMCDG ALVIFDGYDE TAAPLLRGCG
YIKPDPLTST SNVVYIVLDH SDIMESSLFM LTWQQKVISS TPIFPVDQEN FCNGHATIVL
NSTDTTFNLS SPGYPNGYQN GLNCSWIFQS ALPAYHPFLS FSFIDLEESS DCLADYVEVF
SSSDLATWKS FGRVCTFAIR GTYKFHGTPY LKLEFRTDYF QNRTGFTGTV FLRCGGLLTD
PNGVITQPDS LPTVEPGMPV NRLERFESCS WNISVRAGRT IELTFERLNI TVEPADPMVR
NGYVAIMNGI DELSPLLGRY SGTDIPGTIK TSSNRAFVQY RPSIREPNLF RLVYREVSIE
CGGNVVLSAQ LNSTDIVTPN YPEIPPAYSE CFWQVLAPAG QLLWVQVVGQ VLLPRMPQCK
TEYIQLREGL TSNAPELLHS CSGDLSKRIM TKTNALSVKY FNDRTDPNGG VKLRVTLAKC
GGSVRGPRGS ITSKNYPIMG GYPSPAVCEY YLQEGMYGTM NLSFEDLHLP TKGNCSSEDH
VRIFSVLPGR NNTEIELGKF CGTQMPTEPI VSVVPHVKIV FTATTMNTIY RGFKLNYALN
YSRCTHSLVA DSGEITSPGY GEELQTYSFC EWRITVPAGR RIKVEFLDLD IQESGASYLW
MQRLTLFDGV SYQTRIKLIT SNDKSVPIYS SDNRMLIQYL SRMPTGKRGF RLRYSKYLLV
YNGPGPMSPL LGRFCKDSPP PAEPIATQKH LLFVEYHTAR ANASDKVGDF ELRLSSKNFG
CGGTLHPSTS TFGSPLKAGK YLPLQECVWL LQANPGQHIG ARFINRFNLE KSPNCTKDYV
ELFDQRRNRE WVSLGRVCGK DVPPYFNSSG TVMKVVFRTD DSGEADGFTI NPNYPAKYNN
MQVCNYTILA NSSDGGIVFN FLDFDLEDSL VTSLCAYDNL TVYRKLEFAE PITWEKVGTY
CRKTAPARFR VKDRAAIIFQ TDRFIQARGF RFEYRLDTCG ANITSSMRIH SPEQLPPDGT
YRPALTCRWY IDIPPGQKVT VRFEMLEIEH TESCYFDTVE VFRGLEANQD HRLALLCGNL
TGHAPAISIS GSRHGMISFK TESFSTTHGK MSALVLYTPD CDKQITLDDR SPSYRLNVIG
SGNQRVQDCQ YVFQAPNGYT LQLVFDQFHV GSSRNASLAN CTDDFVELRD GGSIFSVLIG
RFCGNDPVAP QTSFGSTMHL RYVTDSALRG TLFDATVRML PSLCGPMHHN LTGGAIITLN
TPNFGGSNKY PPNTKCLWLL EASAGKQVEI QFLQLDLQQF DENSWECKDY IGIRDASGTR
YANAYHVYCG NNYLPSTYIS IVNRVYISFE SDASIEAKGV SLRVHESNLC AKHYTALQGR
IVQTEMLKDQ RCTITVQVPQ NYTIAVYFNT FYLYNVDCAD HALKFYGGPE ERADQLLGEY
CHFATPNPIF TNGNYLRIVL PATDRDFVSL QLDATYVATD QGQGCGGELY NYGGVFSSPL
YPANNRTRME CLWTVTVPNN LVVALRFDVF DLGSKSSCAT DYLQILDRTS DESSVDGANA
EKDTVVRQHC GGDKPANYIG SGSTVRVRYR KTQNFAGVGW MIKFMGIEKG AGVNEY
//
