ID A0A182Y4B0_ANOST Unreviewed; 883 AA.
AC A0A182Y4B0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=dynamin GTPase {ECO:0000256|ARBA:ARBA00011980};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI03296-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI03296-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI03296-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR AlphaFoldDB; A0A182Y4B0; -.
DR STRING; 30069.A0A182Y4B0; -.
DR EnsemblMetazoa; ASTEI03296-RA; ASTEI03296-PA; ASTEI03296.
DR VEuPathDB; VectorBase:ASTE008060; -.
DR VEuPathDB; VectorBase:ASTEI03296; -.
DR VEuPathDB; VectorBase:ASTEI20_034690; -.
DR OMA; MQMVQTF; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR CDD; cd01256; PH_dynamin; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF212; DYNAMIN; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW GTP-binding {ECO:0000256|RuleBase:RU003932};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408}.
SQ SEQUENCE 883 AA; 98202 MW; 93F5EFCE06C8E866 CRC64;
MESLIPIVNK LQDAFTQMGV HMQLDLPQIA VVGGQSAGKS SVLENFVGRD FLPRGSGIVT
RRPLILQLIN GTVEFGEFLH QKGKKFSNFE EIRQEIEAET DRITGSNKGI SNIPINLRVY
SPHVLNLTLI DLPGLTKVPI GDQPADIENQ IKGMIFQFIR KETCLILAVT PANTDLANSD
ALKLAKEVDP QGVRTIGVIT KLDLMDEGTD ARDILENKLL PLRRGYIGVV NRSQKDIEGR
KDIHAALAAE RKFFLSHPSY RHIADRLGTP YLQKVLNQQL TNHIRDTLPA LRDRLQKQML
TLEKDVDQYK HFRPDDPSIK TKAMLQMIQQ LQSDFERTIE GSGSALVNTN ELSGGAKINR
IFHERLRFEI VKMSCDEKEL RREISFAIRN IHGIRVGLFT PDMAFEAIVK KQISQLKEPI
LKCVDLTVLE LSNVVRICTD KMARYPRLRD ETERIITTHI RQCEQKAKEQ MMLLIDYELA
YMNTNHEDFI GFANAQSKTE NAVKTGTRNL GSQVIRKGHM CIQNLGIMKG GSRPYWFVLT
SESISWFKDE DEKEKKFMLP LDGLKLRDIE QGFMSRRHTF GLFNPDGRNV YKDYKQLELS
CESTDDVDSW KASFLRAGVY PEKDTPANGD EESSESGPTG QSLDPQLERQ VETIRNLVES
YMRIVTKTTR DMVPKAIMML IINNTKDFIN GELLAHLYAT GDQASMMEES ADEAQKREEM
LRMYHACKEA LRIIGDVSMA TFSTPVPPPV KNDWLSSGLD NPRLSPPSPG GPRKAAPQQQ
GSLGSMGAPA GRGPPPAPAS ARPAPAIPNR PGGGGAAPPL PGGRPGGQAL PAPLIPSRPG
GSAAGMAQML PASTRQQINQ QVGQAVTNAA MNELSNVFAS KFK
//
