ID A0A182Y5C1_ANOST Unreviewed; 356 AA.
AC A0A182Y5C1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=FAM86 N-terminal domain-containing protein {ECO:0000259|Pfam:PF14904};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI03657-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI03657-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI03657-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. EEF2KMT family. {ECO:0000256|ARBA:ARBA00005511}.
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DR AlphaFoldDB; A0A182Y5C1; -.
DR STRING; 30069.A0A182Y5C1; -.
DR EnsemblMetazoa; ASTEI03657-RA; ASTEI03657-PA; ASTEI03657.
DR VEuPathDB; VectorBase:ASTE008957; -.
DR VEuPathDB; VectorBase:ASTEI03657; -.
DR VEuPathDB; VectorBase:ASTEI20_035624; -.
DR OMA; CWQASCD; -.
DR OrthoDB; 49253at2759; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029426; FAM86_N.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF164; PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT; 1.
DR Pfam; PF14904; FAM86; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 22..103
FT /note="FAM86 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14904"
SQ SEQUENCE 356 AA; 39581 MW; 334C80E21C73E125 CRC64;
MKPNDSLKTT AENHKPADGS PLKLVSKQFL CGTPVRSIRW HGLFERELSW DEQAALLDAT
VDHPLVLRYP LGAEYQAAFL KHIIAQLSSM NVEHHDRMYE KYCAMLSPGT ELPLDDPSIG
LSYKHYELPH GQGVISLKES GAFVSDGTTG LCSWQAAKAL CEHISNNRDD FHGRNILELG
SGVGLSGIYL AKCYEPSIIV MSDCHSSVLT ALKENVRLNF PGAASVECDN PLVSLLLDSG
NTLMGVMDLD WQYISASNLS QLIEPDVIVA ADIVYDHTLF PALLSTLNYI FCLSNNRCKF
VLACTERNQD TLNEFLQLLI TAKFRINEET VSPSRHFHWD SSASTIRIFT ITRAFS
//
