ID A0A182Y8I4_ANOST Unreviewed; 573 AA.
AC A0A182Y8I4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=N-terminal Ras-GEF domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI04770-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI04770-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI04770-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A182Y8I4; -.
DR STRING; 30069.A0A182Y8I4; -.
DR EnsemblMetazoa; ASTEI04770-RA; ASTEI04770-PA; ASTEI04770.
DR VEuPathDB; VectorBase:ASTE002942; -.
DR VEuPathDB; VectorBase:ASTEI04770; -.
DR VEuPathDB; VectorBase:ASTEI20_038219; -.
DR OMA; EQENECA; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF349; RASGEF DOMAIN FAMILY, MEMBER 1B; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076408}.
SQ SEQUENCE 573 AA; 63414 MW; 2041E804B075CCA7 CRC64;
MYYYASKLSA VACGTRCRQG LARRQRTNRT NRQGGKKDDD EDSDDNSKDK KAPLSSFFCE
STNDTIVISV KSSEQPEVCC ESTPTLAHTQ GSLGTGGVMY GNGTIVSGPL ESLIDLLMPG
NVEEFDQDYV FSFLLSARFF IRSYELLGKL LESIPEPEPL ERIVPLLGVW TRMFPYDFRD
ERMMNHVKHI VARCADTKLA NVVPQLLCAL LARLTELENH EEELRSYQST VDNKTESISW
PTATQLAQLL CRIERNLAKH VGPEEFVQCS PNLLKDPNRE DFTPKLASSG AAGGGSSGTG
HATSLDGKKT CNLESYLEWS ARLRLLVANE ILKCRNIQDR NKQFELWSGA AQYCLLVGNY
NSATAILESF DLPPVARLQV TVSEFIIFET EMCAFDCKSK CNATGRMWSK LSSTTSQQLD
CMQRHAEGCG SLWSKQTEQH GNGNTDGRRS VLQPTLANGS PKPSTSASSA TVSTGSGVTR
STSNEWVVIP VFVDIIKLAL KAREDCCVRL PNGHINMTAF DRLAAIVGAF TRHMIQVNQT
LPDVGQYATL CQFMQSCKLL NETVCLAFDR PEP
//
