ID   A0A182YCN2_ANOST        Unreviewed;      1222 AA.
AC   A0A182YCN2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ASTEI06218-PA};
OS   Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI06218-PA, ECO:0000313|Proteomes:UP000076408};
RN   [1] {ECO:0000313|Proteomes:UP000076408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX   PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA   Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA   Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA   Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA   George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA   Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA   Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA   Sharakhov I.V., Tu Z.;
RT   "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT   stephensi.";
RL   Genome Biol. 15:459-459(2014).
RN   [2] {ECO:0000313|EnsemblMetazoa:ASTEI06218-PA}
RP   IDENTIFICATION.
RC   STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI06218-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC       {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A182YCN2; -.
DR   STRING; 30069.A0A182YCN2; -.
DR   EnsemblMetazoa; ASTEI06218-RA; ASTEI06218-PA; ASTEI06218.
DR   VEuPathDB; VectorBase:ASTE011667; -.
DR   VEuPathDB; VectorBase:ASTEI06218; -.
DR   VEuPathDB; VectorBase:ASTEI20_033185; -.
DR   OMA; QLCQHIP; -.
DR   Proteomes; UP000076408; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd11394; bHLHzip_SREBP; 1.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   PANTHER; PTHR46062:SF1; LP12374P; 1.
DR   PANTHER; PTHR46062; STEROL REGULATORY ELEMENT-BINDING PROTEIN; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076408};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   1222 AA;  133865 MW;  8A5165B3151F9664 CRC64;
     MDQDRGWNDP FQPPPGLFFS NGNFEEEDIG MNDISDIGDI TDIYQMNEEK LLNIMGEDFL
     TNFGWEETLG DPSAAANALP AANGSSVTIK EECLAQEASP GPSKGEPMFQ ASAGATPKEP
     VLLAPKPTTP SSVPLLSPKE EKKLVMCAPA MLQSMHPAST AASQPHVQHV PQIHLQAGNH
     LVARSVILAP NRNTVTSSAA PSTDTPTTQT TFLLQNARTP AVTQTYTKKI APAPTGVGVS
     VAPQPTATQP QPAPATANLM PSITNVRVQN LMPQLITLQT VDKQSVFLPA NTPLIYTNGN
     VHSIATTAPA ASMVTVKPNP NLHTLVNTPN GPILAAGIPV VLDAPAQQQP PQQQPQPQLA
     PDVQPKVQLS RLPPSGGVPK VKEVKRSAHN AIERRYRTSI NSCIVELKNI VVGVDAKLNK
     SAILRKAIDH IRHLQKQNNL LKQENMAYKM RLADQKHSLK DLLVGQQHLA DEMMVGPITP
     PRSDESNPAS SPAHSDSSMP GSPFTGSGSL SSAGGDDLLD DEMLSGLGGM SSNARLTICM
     FMLAVLVVNP FGSLLSLASS EQPEELGTTR RILAVEESLS WSRLSSTLLL ALVNFMFLAF
     CLVRMLVYGD PILLPRSRAS TDYWKHKRQS DVEFRRGNAD ASYREAKLCL QSFGLSLPST
     RFERVSTTAW QFVRMFFHRL YIGRWLSRRT GGLFKPEGER MHALHSAREL ALLYHRLNQL
     HLVTNRTDAN GLMMSLCAVN MAETAASVIS VDDTIEIYLL AALRVKRSYP RLLQYYCRYY
     LAQAKQLASD HTSRRFRWLF TPYGFRFLTT NRFRYGERTD GSTALFTTLC NSADPIEYVM
     REYRLNLLQQ ALQLLVGSGH ERTVRDGASN GTGSPGKGNT GTAGVLINGK DTKEDHHGSK
     SSEVADLSST GSGVSGDILY FTELLQDTFG LEKPVPFDGS CSVHGPECCY DELAHWWCNL
     LRVAGFWLLG EDELAEAMYV QVETVPAALH QTEDPLPRAL LLAFHAKRGL INKTESSVEM
     IFANCNASSR FLEDSLTGNI CKTPSRLKLL SQLLACDWLL EARTALWEIE KDTRYNQQTH
     QTVPGKILAA FQTDLNLLRL VTSKFPNAQS RVFLYEAVCR LMAGAAPGPT QQLLDRSLRQ
     RNSRSSLICG KDRSAQLEGG RERAAALYVA CKHLPAPCLS SPGERAGMLE EAAKTLEKIG
     DKKRLQQCYQ LMKSLGSGSV TN
//