ID A0A182YCS0_ANOST Unreviewed; 1430 AA.
AC A0A182YCS0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Phorbol-ester/DAG-type domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI06256-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI06256-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI06256-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
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DR STRING; 30069.A0A182YCS0; -.
DR EnsemblMetazoa; ASTEI06256-RA; ASTEI06256-PA; ASTEI06256.
DR VEuPathDB; VectorBase:ASTE011624; -.
DR VEuPathDB; VectorBase:ASTE011625; -.
DR VEuPathDB; VectorBase:ASTE011626; -.
DR VEuPathDB; VectorBase:ASTE011627; -.
DR VEuPathDB; VectorBase:ASTEI06256; -.
DR VEuPathDB; VectorBase:ASTEI20_034213; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd20834; C1_nPKC_theta-like_rpt1; 1.
DR Gene3D; 3.30.60.20; -; 2.
DR InterPro; IPR000961; AGC-kinase_C.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR020454; DAG/PE-bd.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR017892; Pkinase_C.
DR PANTHER; PTHR22968:SF14; -; 1.
DR PANTHER; PTHR22968; PROTEIN KINASE C, MU; 1.
DR Pfam; PF00130; C1_1; 2.
DR Pfam; PF00433; Pkinase_C; 1.
DR PRINTS; PR00008; DAGPEDOMAIN.
DR SMART; SM00109; C1; 2.
DR SMART; SM00133; S_TK_X; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 2.
DR PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ SEQUENCE 1430 AA; 156280 MW; 774FC348680D4383 CRC64;
MIFTGAHGRR RAGNGQSNSQ RNVRGSRSNA QEQARGRNQS QRPYLSRDQQ QLSLQSVVSS
SSSSTNSSYY SAYSEHQPLV RTSSSSSVAT VAPLLPLGAS SGSLTTQQQQ QQQQQQQQQQ
QQSQSAQQQQ SALQQAQFVQ KTKARDITKR RGAIKHQRTH EINGHKFVAK FFRQPTFCAF
CKEFLWGFGK QGYQCKTCQT AVHKKCHDKL LGTCSESSFN SESTIYLRER FKIDLPHRFR
VYTFMSPTFC DHCGSLLYGF FRQGLKCEVR HRLVRSIVDD DNPVPLRIRN HSVRCRPLFV
DGLQKMPLYS ELYHNFVGNT PIIPTPIVSV GSSTYSPPTY VGVSRAFPNP LSSASSRTAP
SFTRGYVPKL TPITETPLTS TRIAALGRVS SPKFLGGHHH HHGHSSPTYQ KPRRTINTAD
IDVSASKYAG GTRTPLSTHH RSLALLESSC SPTNYSGPSS PPDASSLSSI GTATINLSET
ERTVGGALSS VTPLSTRDQE LNERSEQRRA RSTINRNRTV VRLNTIRARS KSRGSRGSTE
GRDRLTLPEV GSEPTFDEEM LLLEPSMVRP GGGSSWRDNF RDELSLRPRT RTEPSKSPGE
LLLEKHLIRD GESAAVSTTE PSYPPTRSPV PKRRGTIRRK SAVKIPSFHE ICADISSDKL
DDDLNAGELR RRASQLIEDE LLQFQEELKK AATGANNLAP DILEERLKEA LEQQIAQDSG
VEVAEKRKQK KIKRTRTKVL PVPTPDEQEM EPKLASEPVV VVENAAPPRI VAELESIEEC
TVFKLPKKKK KQPEDTGVVK KSTTPGGLRK ETTEHGRTEP ELQQVQVVIV DRPQSHSADL
TNGMQDASKQ ASTDAEGKGV VEGAGPADTP PSPTILPKPN AEPRKLAKTG IKTYTKLNQI
TLNMGVKGTE VEVKECQKCQ SAIVSEALPV PVAIVTATPT PKPAKQPIAN GAKLTKNKFG
TLDNLSDLSA VDVRDRNNNA GVVKPSVVKP KQTTVAVAAA AAAAAVATSA DKQKVLFSSS
EEDGTGVPAS GVGSRIDNDS ASETSFSGVE DDWSSEEEED DDDDMANDKL EKKKPFDPTK
RVKLNFDQMR KCYSKEEKSP IVLVARPRPL WKVKRHGHRH NRKADLTSSS SSGSGSSSDD
ESTSTSTTTS SGATSSSTNN TTDQTSSEAV SILDGATSDI NTDSSVNSST GGKQKGKGQQ
AKAKGQKGKP DPFSDIYDNP MVIPLHAEPR TSSRKSGGSF VPPPARDENN NTPADLDEDE
RARSIGGGHE VRSASTSSHD SGFYGGGTAP ISPKKALDCD VNCHKKCEKL AANLCGVNQK
LIVEALSSVR RGKCYQLLTT RLDNHKCQQS CSPGVHEARD SPSKVPPSAN PAYRIETPVP
SRHPLDTQYF DKQFTRERAR LTPIDRNILA SMDQAQFEGF TYTNPNNTLT
//
