ID A0A182YD26_ANOST Unreviewed; 2081 AA.
AC A0A182YD26;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=PDZ domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI06362-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI06362-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI06362-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR STRING; 30069.A0A182YD26; -.
DR EnsemblMetazoa; ASTEI06362-RA; ASTEI06362-PA; ASTEI06362.
DR VEuPathDB; VectorBase:ASTE004883; -.
DR VEuPathDB; VectorBase:ASTEI06362; -.
DR VEuPathDB; VectorBase:ASTEI20_035944; -.
DR OMA; YHSPQTL; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd09512; SAM_Neurabin-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR040645; Neurabin-1/2_PDZ.
DR InterPro; IPR043446; Neurabin-like.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR16154; NEURABIN; 1.
DR PANTHER; PTHR16154:SF6; SPINOPHILIN, ISOFORM J; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF17817; PDZ_5; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408}.
SQ SEQUENCE 2081 AA; 226344 MW; C1839F9EC398684B CRC64;
MEKSTATAHP ASAAGPKVSQ IANLFQRKPV EQLAQDNIPT RGDRPTTDSS TAATHSPTAT
VVRTESHAAR FNNARALFEK LGEGRVNRPP PFSIKMSHSS SKEDNLSDIG SGPDRSPSPK
RKQLQQQPPS AISNGIGKLD SNRILNQSRL KSEKPEKPEK PERKFNSREL IEKQKNWTSH
FSKTRTTKGS GASEFNRCDI IRTVPGTGII AGAGSNTTTA TPSVGSGPTT NGNYSAIPNG
SSKEQLPFAA ERNGPAVNHG HAPLISSHHR LPSPSEPPPS PPKRQTPPPP PPEKGPRTAN
LRQNSFPSPT KTPPAVPPHA TDPSSLSPTK LSPEKLKPPP RQAEPPPAST ATPHANLPPV
APVRSSTTVL TTVNHHQQQQ QQQQLVSGAS IEQQVPPPPP EKTIRKKSLE GNLDERQPPA
GNGGNAASFK YPELGALARR QSSEKDTGSG GLTSPAHAIS SSPSPGASAS SGPSSPIHTE
DEKQENESTE KLMKVGSSER EDSRAEDTPP ANEMKTVEEL NGKSSRTDDE HSGEPQQQQQ
QQQQHGGVTR RTKVSSICFD VPAAGLGNRP PSIISSSTTT DEGGFNEPSP EIKAKLKPAY
EFDLPLPASP PRKLPIGEDR SPVGSPAEAK LTYADLGYRV RPDGTECDEI YGEVDVYRSA
NTSSSINGKQ QPGGVPLNTA ALNRSQPSGA SGSSVPNGQG SAQLAEPQVA GVPPAIINGR
SAATDRVLYA SILPSSLGDN SSTTTTATDS ELAFMDGERD EAKILDFDEL SEMGEKGYHS
AQILLDPTRI TLSELEDDYS TKTLPDPPSL ASMRPPPIPE GPPLDLQDSL KFADASDNEQ
DSLLPDEMTA DEAERLLSSR QRPLLSDEQA REVEQILLNN QAKAETDEPP LPRVVASPRQ
QAPSVPEREP VPVQAAKPVQ QTQLPPVPLP PQPKQAPPTT TATSDEPDWL KDVLEAPKNA
TSSTSTVGSS MRDKPPPPPP PTSASRNNST TSQQEDASIG NNTTDLLNQT ILDSSSILAD
SYVDTGDSIP SVTTTTSDSI NLSKQEESAG ETGALEDEGE ATQEDEAQER EMVSGRQAAV
HRQHVGESIS EADVSADDES NHSAGFYIPE YPPIRCKEVY VNPDGVHFFE DGNFWMEVPG
LIEAERELDD DDLRGYVKKN TKVKFSSNPM QVFSTFSVND YDRRNEDVDP VAASAEYELE
KRVEKMDVFP VELMKGPEGL GLSIIGMGVG ADAGLEKLGI FVKTITDNGA AARDGRIQVN
DQIIEVDGKS LVGVTQAYAA SVLRNTSGLV RFQIGRERDP ENSEVAQLIR QSLQADREKE
ERVKRQLEDY IRRNAEISED STLPVSANSS VSEGPVSPTT NAAESLFETE AARSSDVESL
RRILQENLKT IALHEGDILN LKQQLIKYQQ TCNEAELLNE RVKQTERELA NIKKEANNYQ
NMLQQSQAQY LVLEKKYSRV KKILRDYQHR ERDMIQFQEY YLQHLQEKDT EYNALVKKLK
DRVISLEQEL QETQRKAGFP VILPYDSASL KLTPQMSRRQ PPKPVFQKLE TDLSDTEFSD
LSPDGEGEDG KTATVERKVP PSTKDDDLDV AVPQHELLDN SLNKGKSDLV ARGGLAKRNL
PGKRSHSNSG SDCALDESDE EGHMTRSTTG GTEGSHEYSG LYSTPQIVNR KVATLKGEDS
GPPVYAQVNK ERSSGGAGHP DQQQHTTIPN IYRAAVGSDN GKLNSSYGSD LNASSYDSDL
GSSTDKLKDS GLSSDSWMYP SRRPKGLKGI TPPLLAEQLK ERLAEREGRR GSGGGLIDDG
SSRDSSDDYS EINQQQRHIS PAASLSQNLL VEIKKAVHEA QPKGGNGPWQ QQQQQSQQQQ
QQQGQSTSGG PAAGSQGPPS PSSVSSGSTS PGAYSPSRTL DLSGSTSSFS SDRIRDTHQW
KNGPVEEWSN EQVMCLVVMG KMMVLEIESE TNFGTDSGIG IGTVTNVLHI TFSFFSRINR
TFPFPNQVCQ WLLGIGLDHH IPAFMQHSVE GGALLQLDKP DFKILNVGGD DKKLLKRNIK
ELRRLNEKER KQNEKERRER EKLFKKAEKK AEKEQKKRYQ K
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