ID A0A182YKF9_ANOST Unreviewed; 1292 AA.
AC A0A182YKF9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Regulator of G-protein signaling {ECO:0008006|Google:ProtNLM};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI08945-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI08945-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI08945-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR STRING; 30069.A0A182YKF9; -.
DR EnsemblMetazoa; ASTEI08945-RA; ASTEI08945-PA; ASTEI08945.
DR VEuPathDB; VectorBase:ASTE016094; -.
DR VEuPathDB; VectorBase:ASTEI08945; -.
DR VEuPathDB; VectorBase:ASTEI20_044067; -.
DR OMA; IKSDMYR; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01817; RBD1_RGS12_like; 1.
DR CDD; cd17067; RBD2_RGS12_like; 1.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR046995; RGS10/12/14-like.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45945; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR PANTHER; PTHR45945:SF3; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR Pfam; PF02196; RBD; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00390; GoLoco; 1.
DR SMART; SM00455; RBD; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50877; GOLOCO; 1.
DR PROSITE; PS50898; RBD; 2.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408}.
SQ SEQUENCE 1292 AA; 136149 MW; 2D2C28F07A5B12B2 CRC64;
MLLTSHDHVG FKMMGFIKED EIYASSIGNG ETEADQRGST IVGSVGRGRQ TIVPEINVIA
PPTAEPEQDG KQINHNASPF RRWGQSSLRS RSTEHRTPTN GSSRRPSSLA ASESDVYTKS
IDDDYSSTKS GYNPYTGGVD TLSTESAAGV VATGGSTLGT AGSGGSTAPS TGPTGVASWG
TSFEKLLEDA GGLHTFSEFL KKEFSAENIY FWTACERYRQ LTEREERARE AQAIFARHLE
SGCSEPVNVD SIARNIALEN LPQAEPTLFA AAQKQIFNLM KFDSYQRFIK SDMYRVCQEA
EAKGQVLPYP GEQLDPMLRT SSTMATASGA NAAGVTKLKK SLSNAEDRRR KSLLPWHRKT
RCKSKDRGDS DASKKDNGKG TGSGGTGVGE KSSSGMATSG GGSSSNTLKL LSTNSTSDIH
SSRSSLASFD AAIGGKSYDP DDSRNTLCRV ILSNGATTVV QTRSNETIKE LVERLLEKRG
IVYNAYEAFL ASGTKPLDLD GPSVSLAGKE VNIDQRVVFK LSLPNRKMIS VKSKATKPLA
DVLRPILYKY NYELDQMKVV VQSTVDVFLD MTQPVTTVDG LCLHIRSANE PPGGPVHPEL
GRPLAGARPV INTATHQQIV HHFQQQQQQL LNSQPAALGT NQQQPPHPFV IPSSNPPSYA
VATNTKSQQL FGSGTAASAT CNTNMSQNQT RAKEQTESVK DEQTGPARPG QQELNTLDEI
TNKVFNELMN GKTASNGAVG KGPPDVDCTS DTSSTRRDRF RRRGSNAAPS ESGRGAKSKK
CSTGGSEDGG ESVNNLGIKK PIIAKLKAGV KLQIPTRSQN DELLEGLKRA QRSRLEDQRG
TEINFELPDF LKDKENFSSA SAASLGNAST VAAAAAPSTA GPSKLTRSKP ARRSEATTPT
SEFVGGSLQQ INKPQPAPRL SITGQGGRQN PSGPGSPVHA AVSDSHLNLS TQCNASPLPQ
DDPFHVHGGG GGSQSETSYA DTTLVFTHAR PYNGQPSVAA TPRSTISSNS VSHHHGPGDH
SSDSSTAADG DLTTLGCCEH HPHELSPDSS PPNHANHLHP MHYHTAGASG TPNSGSGTIT
STTNPYPLVH YPSHNHHHHH VHPHHHPHGQ HYHHHHHNHS AGTRYQTATP VANGLDGQTG
ASAADSQKGP PPLPPKPKIL PMKPSNWGHP VAASYAPGPP GTGGNDVVPG SLTNGTTTAP
GNSPNPSSTL SNHHGGVGTS SNGITVSSTA AHSDGSAVGG GAIVREGNRR TSGGGTTDSG
SSSGTIHSAS SASAISVAVA QARNSPTQGP LG
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