ID A0A182YNK4_ANOST Unreviewed; 490 AA.
AC A0A182YNK4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ASTEI10040-PA};
OS Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI10040-PA, ECO:0000313|Proteomes:UP000076408};
RN [1] {ECO:0000313|Proteomes:UP000076408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA Sharakhov I.V., Tu Z.;
RT "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT stephensi.";
RL Genome Biol. 15:459-459(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASTEI10040-PA}
RP IDENTIFICATION.
RC STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI10040-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC ECO:0000256|RuleBase:RU000679}.
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DR AlphaFoldDB; A0A182YNK4; -.
DR STRING; 30069.A0A182YNK4; -.
DR EnsemblMetazoa; ASTEI10040-RA; ASTEI10040-PA; ASTEI10040.
DR VEuPathDB; VectorBase:ASTE010336; -.
DR VEuPathDB; VectorBase:ASTEI10040; -.
DR VEuPathDB; VectorBase:ASTEI20_031919; -.
DR OMA; CWRRDDH; -.
DR Proteomes; UP000076408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR PANTHER; PTHR11690:SF285; PICKPOCKET 3; 1.
DR Pfam; PF00858; ASC; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000076408};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|RuleBase:RU000679}.
SQ SEQUENCE 490 AA; 55942 MW; 0EE52BD8E30A23E5 CRC64;
MVENPEKTFT AKEATFNQKL FAVLHVPGLQ YVFDQRKHPL ERLFWVLVIL ASIRGMLFLG
QYQYARYGAN PTAIQMDKNY RDWIGIMPGL TFCFHDRIDW KRAHEYLERI QLTGHGEATR
ESLTANETTG TSRYLAEFVQ TLVDATATEL GNLSRFLNDS RLAADVNVLE LISTVHPNHD
IAINSFQPGH GGLLQVHQIV TERGICYALN APLAFLQHAT RTGQPLASEK DVPGWAPISC
EFSKHHCYMK LDMYRSTVSY AIHSPYEVAT SDQLFTHVDE SDELVAVYSV LETVANERLK
DLTVRQRNCF FYDEVYERLP RYSHNLCIMS CRAKRALAAC RCRPHFYPFA EGPACTVQGL
HCLQQHPDWY TADVDCKCLK SCTDVGYYVA SLSKTQWTAE GGIPFTHKAS LRWEILQPKT
RLRRVLIFSY EDLLVSFGGA VALFLGKNGF YLSKVAEFLV IEFSGWVRRK FFVRKAVKKD
IKTPHLAPSK
//
