ID   A0A182YNM0_ANOST        Unreviewed;       651 AA.
AC   A0A182YNM0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE            EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
OS   Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI10056-PA, ECO:0000313|Proteomes:UP000076408};
RN   [1] {ECO:0000313|Proteomes:UP000076408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX   PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA   Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA   Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA   Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA   George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA   Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA   Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA   Sharakhov I.V., Tu Z.;
RT   "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT   stephensi.";
RL   Genome Biol. 15:459-459(2014).
RN   [2] {ECO:0000313|EnsemblMetazoa:ASTEI10056-PA}
RP   IDENTIFICATION.
RC   STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI10056-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class 1 subfamily. {ECO:0000256|ARBA:ARBA00009701}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A182YNM0; -.
DR   STRING; 30069.A0A182YNM0; -.
DR   EnsemblMetazoa; ASTEI10056-RA; ASTEI10056-PA; ASTEI10056.
DR   VEuPathDB; VectorBase:ASTE002653; -.
DR   VEuPathDB; VectorBase:ASTEI10056; -.
DR   VEuPathDB; VectorBase:ASTEI20_037039; -.
DR   OMA; VIQFHYM; -.
DR   Proteomes; UP000076408; Unassembled WGS sequence.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   GO; GO:0048666; P:neuron development; IEA:UniProt.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR46047; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F; 1.
DR   PANTHER; PTHR46047:SF3; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000076408}.
FT   DOMAIN          8..276
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          189..267
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
SQ   SEQUENCE   651 AA;  72824 MW;  373682FC6673B198 CRC64;
     MLIYFLFLPF PLQDIRERSD IQARAKKFST DESKKLDNRR LNRYRDVLPY DHSRVALKRG
     EGDYINANLV KMERAGRKYI LCQGPLPLTV GHFWVMVWEH DSRAILMLNK LIEQTTVKCH
     QYWPAKIGEQ HRLELTDVQL SVVHLKCVEY KNFCKRTFRL TDMETGKSRE VIQFHYTTWP
     DFGIPSSPVA FLQFLKEVRD SGTLDRDVGP PIIHCSAGIG RSGTFCLVDC CLVLVDKEGE
     DRVSVQDVLL ELRQYRMGLI QTPDQLYFSY QAIIEGMKRM NNSSFEEFEE LSVVSSSSQQ
     NSDQEDNEDT PPPLPPPRTH SLTSKPLPVI PTSESVHEEF LLGSSNGGDR DKVNNLVNLE
     KSKQFEMGDE NHHHHNNHHH KRNDSGNNHH NNHHHHLYSN RPLPPIVRDS SLYKVNELDS
     DGGGGGNDGD GSSDGSDSNA MSSEDELIEE NDSDIGEAED DEEDELKNRG AIGRDVPSDN
     SDNIKSSLLD ESSSTTTGTT TTTTTSTSGG GTSTGISSST SVSTSSSTTA SAIGSNSSTL
     ESKRGGVDSK SSEQQAFNAN SSLPPLPNGA LDDGDDPISS PERELSPNAE LRRRKRIERM
     SAMEEKIREI KRKRKEVESK GSPKKRRLLL FSIAAGVCFS VLCVYLYTKQ M
//