ID   A0A182YP43_ANOST        Unreviewed;       974 AA.
AC   A0A182YP43;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Multicopper oxidase {ECO:0008006|Google:ProtNLM};
OS   Anopheles stephensi (Indo-Pakistan malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=30069 {ECO:0000313|EnsemblMetazoa:ASTEI10229-PA, ECO:0000313|Proteomes:UP000076408};
RN   [1] {ECO:0000313|Proteomes:UP000076408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Indian {ECO:0000313|Proteomes:UP000076408};
RX   PubMed=25244985; DOI=10.1186/preaccept-1262842421127991;
RA   Jiang X., Peery A., Hall A.B., Sharma A., Chen X.G., Waterhouse R.M.,
RA   Komissarov A., Riehle M.M., Shouche Y., Sharakhova M.V., Lawson D.,
RA   Pakpour N., Arensburger P., Davidson V.L., Eiglmeier K., Emrich S.,
RA   George P., Kennedy R.C., Mane S.P., Maslen G., Oringanje C., Qi Y.,
RA   Settlage R., Tojo M., Tubio J.M., Unger M.F., Wang B., Vernick K.D.,
RA   Ribeiro J.M., James A.A., Michel K., Riehle M.A., Luckhart S.,
RA   Sharakhov I.V., Tu Z.;
RT   "Genome analysis of a major urban malaria vector mosquito, Anopheles
RT   stephensi.";
RL   Genome Biol. 15:459-459(2014).
RN   [2] {ECO:0000313|EnsemblMetazoa:ASTEI10229-PA}
RP   IDENTIFICATION.
RC   STRAIN=Indian {ECO:0000313|EnsemblMetazoa:ASTEI10229-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the multicopper oxidase family.
CC       {ECO:0000256|ARBA:ARBA00010609}.
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DR   AlphaFoldDB; A0A182YP43; -.
DR   STRING; 30069.A0A182YP43; -.
DR   EnsemblMetazoa; ASTEI10229-RA; ASTEI10229-PA; ASTEI10229.
DR   VEuPathDB; VectorBase:ASTE005343; -.
DR   VEuPathDB; VectorBase:ASTEI10229; -.
DR   VEuPathDB; VectorBase:ASTEI20_041952; -.
DR   OMA; SIFAYHH; -.
DR   Proteomes; UP000076408; Unassembled WGS sequence.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd13858; CuRO_1_tcLCC2_insect_like; 1.
DR   CDD; cd13884; CuRO_2_tcLCC_insect_like; 1.
DR   CDD; cd13905; CuRO_3_tcLLC2_insect_like; 1.
DR   Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 4.
DR   InterPro; IPR011707; Cu-oxidase-like_N.
DR   InterPro; IPR001117; Cu-oxidase_2nd.
DR   InterPro; IPR011706; Cu-oxidase_C.
DR   InterPro; IPR045087; Cu-oxidase_fam.
DR   InterPro; IPR033138; Cu_oxidase_CS.
DR   InterPro; IPR002355; Cu_oxidase_Cu_BS.
DR   InterPro; IPR008972; Cupredoxin.
DR   PANTHER; PTHR11709:SF218; FI03373P-RELATED; 1.
DR   PANTHER; PTHR11709; MULTI-COPPER OXIDASE; 1.
DR   Pfam; PF00394; Cu-oxidase; 1.
DR   Pfam; PF07731; Cu-oxidase_2; 1.
DR   Pfam; PF07732; Cu-oxidase_3; 1.
DR   SUPFAM; SSF49503; Cupredoxins; 3.
DR   SUPFAM; SSF57603; FnI-like domain; 1.
DR   PROSITE; PS00079; MULTICOPPER_OXIDASE1; 1.
DR   PROSITE; PS00080; MULTICOPPER_OXIDASE2; 1.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076408}.
FT   DOMAIN          298..406
FT                   /note="Plastocyanin-like"
FT                   /evidence="ECO:0000259|Pfam:PF07732"
FT   DOMAIN          546..669
FT                   /note="Plastocyanin-like"
FT                   /evidence="ECO:0000259|Pfam:PF00394"
FT   DOMAIN          795..923
FT                   /note="Plastocyanin-like"
FT                   /evidence="ECO:0000259|Pfam:PF07731"
SQ   SEQUENCE   974 AA;  110552 MW;  15C7E02B785A999B CRC64;
     MMMISCHCDP SKCQPLSNIS ETSLEPGQRI RRELDPCCEI LRLYCDASAC PPAIEFCDAE
     RTIRPRTTVG TCCTLQRCEN FCEVYADGEI TTRSVGEKWF NMVNETTCMN YECLRNEANE
     TFINSIGIQC NTTCPEGFEA QISHQHCCPQ CVQARCKFDD QFYREGQSWA SPDGCLLYRC
     AKDGGFLSIS SSRKQCPVVG NCPEQNVVER DCCKVCNYTA EPRMESTTAA PVEQEEGVDF
     YEEQSYSNHP CKRVCTLGRK PETCYYRFRL EWYRTLSKAC YNCPYNGTDC DRPHCIAGDG
     VRRNVAVINR MMPGPAIEVC ENDIIVVDVE NHLMGESTTI HWHGLHQRRT PYMDGVPHVS
     QCPISPGTTF RYTFRADNPG THFWHSHTGM QRGDGAFGAL IIRKDNDIHE LLYDHDLSEH
     VITVQDWGHE QGVSLFAAHH HSTGDNKPPN LLINGRGKYF QRFAKTTPLG TTTTTEAPDL
     EEDPSVTTQP EAIPVEEVPE ETTIVDVPTT VAPTVTTLDD VELLQASSNN NLKTVLHAND
     VRHRTKRQSR TVNFNAVVVP ESQHVPLSVF YVDKGRRYRF RLINAEFLNC PVEVSIENHN
     LTVISSDGFG IQPLEDLGSF VSYAGERFDF VVKANQPIGN YLIRFRGLMD CDERFTSAYQ
     FAVLRYRGAP EDTEYESWPP YDYEAPGVQL NSLNRGPGAE NVITIAETNA LDQEDLLLLR
     DQTDYKFYVY YDFYGKDNPH FHVPSLYGFQ QVINNTNRLY TPQLNHISMR MPSIPFLPGK
     DVLDESQFCN ETSVRDRNCR EEFCECSHVI QIPLHATVEM VMIDEGFTFD ANHPFHLHGH
     AFRVVGMDRV SRNTTVEDIR RMDEEGRLPR RLKKAPIKDT VTIPDGGYTI IRFIANNPGY
     WLFHCHIEFH AEIGMSLVLK VGDSSEMLPV PANFPTCYDF KPKLGELGNG TGSTRFTTSL
     LLLAFAVQTL HRLL
//