ID A0A182Z726_BIOGL Unreviewed; 959 AA.
AC A0A182Z726;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 3.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Hormone receptor 4 {ECO:0000313|EnsemblMetazoa:BGLB004934-PA};
GN Name=106060296 {ECO:0000313|EnsemblMetazoa:BGLB004934-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB004934-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB004934-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB004934-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013073570.1; XM_013218116.1.
DR RefSeq; XP_013073571.1; XM_013218117.1.
DR RefSeq; XP_013073572.1; XM_013218118.1.
DR AlphaFoldDB; A0A182Z726; -.
DR STRING; 6526.A0A182Z726; -.
DR EnsemblMetazoa; BGLB004934-RA; BGLB004934-PA; BGLB004934.
DR KEGG; bgt:106060296; -.
DR VEuPathDB; VectorBase:BGLB004934; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd07168; NR_DBD_DHR4_like; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR48092; KNIRPS-RELATED PROTEIN-RELATED; 1.
DR PANTHER; PTHR48092:SF18; NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 232..307
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 725..959
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 959 AA; 106779 MW; 17DE37BF60D42707 CRC64;
MSASRQPSPL SESLKSSPMS SLSSSSSGVI SSTSLSSSPS PMPKVSSAAS SMTSASPVIL
SCPQGYLMQL SSGFNCSSNG GMKLIPMVSI SSSMFQSVST PMFITTNANG YIVSSTKDSG
FPQGTPLITY PTLDGAKAVS VKDVLQLDKP QITIPTEDSF TTLNLPSPKF KQPRREETKL
EKDSEFISHY TNGAFVYRGH LAENPHNLKP ANADSMTLSS GIKCEDSDGE EPLVCAICND
KATGLHYGII TCEGCKGFFK RTVQNKRVYT CVADSNCEIN KAQRNRCQYC RFKKCLKMGM
VLAAVREDRM PGGRNSGAVY NLYKVKYKKH KRRENSERNM RNQKLSFPTC KLEMPETIPG
YPVDNFTSSN SAYESSTGCD SDVVSCHSEK SLTSYDQFHG YHHTRHLNNV PTSSTSLYSI
SHNEYSSAHS GHLQSASSNG PKSYHQSRLF DQQTYLPQEG VTHLKIPSPV RQRNLSSSMS
DACSLPSKGI TVELGKVALC SSSRHQDQCL ERSHSSHTMK SYNYDNEQSS PNAHRCGVET
CQEQALTSFS GHQLTSSYYN HKHRVSPNQS TSEYTSSSFH GAEHNTCSPD VQSDRTIQKN
VQDSNSNQLK NSKNHHVYID MNNLPGVKQE VERIDDYRQS KVINLQKSCV REINILPPSP
STSPPNDCQT KAHSNHLSPN SSHHFKYPAS PLQNENGRSI SSLHPPTHQA SATATSGGLS
FFNMPVSSLI SDLAKNESLL SIANDYKISQ FTGTEEVVAQ ALCQVGGKIV MRFIQWMKQL
PFYRDIPKEL QTKILMSKWH ELLLLIMVSA GPVGKHLKKS DYRPTFSELY HKNMLRMQDY
LDKSFNKFFT LDQLQSDIGE IMEKVTAIMT YFWELGITKK ELMCLKVILL LNHESIKKET
KLQHISASYK QALQQYILEK FPSEANRLGD VLSQLPYLQE ASAQLLTSKM IYIPFLLND
//
