ID   A0A183A862_9TREM        Unreviewed;       753 AA.
AC   A0A183A862;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=SH2 domain-containing protein {ECO:0000313|WBParaSite:ECPE_0000315001-mRNA-1};
GN   ORFNames=ECPE_LOCUS3147 {ECO:0000313|EMBL:VDP68550.1};
OS   Echinostoma caproni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Echinostomatidae;
OC   Echinostoma.
OX   NCBI_TaxID=27848 {ECO:0000313|Proteomes:UP000050740, ECO:0000313|WBParaSite:ECPE_0000315001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ECPE_0000315001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP68550.1, ECO:0000313|Proteomes:UP000272942}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Egypt {ECO:0000313|EMBL:VDP68550.1,
RC   ECO:0000313|Proteomes:UP000272942};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAN01040131; VDP68550.1; -; Genomic_DNA.
DR   WBParaSite; ECPE_0000315001-mRNA-1; ECPE_0000315001-mRNA-1; ECPE_0000315001.
DR   Proteomes; UP000050740; Unplaced.
DR   Proteomes; UP000272942; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR   PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR   PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR   Pfam; PF03530; SK_channel; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000272942};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        675..692
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        712..733
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          271..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          513..585
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        513..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        547..585
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   753 AA;  83494 MW;  6C30B188EEF00106 CRC64;
     MSRSELSQTE ALLSESSLTK TLDEEIQTSY TANALGISPP CTVVQTQEVS STDQSIKPVN
     RRTKASRWRT FHKDPVHLDP HSIPNPASSN KSLRQRWYAK FKRDYTSATN VSHVEPVEHM
     SADHRQISRI RSFRKLQRGV VVVHSDTNSR NSGGSVSKNY SLDSTKSDGL LNKTISFVGE
     SVGPDTSEAP LEHYLPALTL TVPVEDVVRV SDQSQRTNTQ CTTSMDHEEQ MEHLCDYCAL
     SQPTVSTGLL GSHNTLSPCV FRRHSHCGCS GSDGSGEPNA GSEQGKDVCP GNSETLTPRC
     PRCQRQTQHA HAYVSRNIYP PTRNRNASCS GIDMLADAIL QTHSRAKGSS VESKTTSRDL
     FNLNRLRIIR RGEGKHLRNS LGEKFKPFPN EPCSAETTSH VSNIRPPMLV TPSVEAEEPI
     PCKDIQFNHR KDKKSVEVPT SVNSVDSVLD RTPGDHSHGT HYLKTKSIDS CTENSLKVPT
     LTQMFPKRTT TIDDEIPLDS RIRRVSMILL SRQHQAAPEN GTTGAERKDT PTCNVPSKDE
     HHPLLTPPTV KSSSSRTRFL PPRQDTDNWS LTSVPRIDSP KTTKQHPAVL GSTIIPLTTT
     LVPTGNAHTI SVGSSTTPNP IVIRPTINGN NDDDRVGKDV HMRYRRLRRP TERYSKGIGY
     HLGRRRHLLE RRRRMADFSL AFGLFGIVAA FLDTELVARS LYSKTSIYSY GMRFLISLST
     IVLLALIVSY HAYDVMSANL ASEASTVTAS IPR
//