ID A0A183A8L8_9TREM Unreviewed; 537 AA.
AC A0A183A8L8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:ECPE_0000330601-mRNA-1};
GN ORFNames=ECPE_LOCUS3303 {ECO:0000313|EMBL:VDP69074.1};
OS Echinostoma caproni.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Echinostomatidae;
OC Echinostoma.
OX NCBI_TaxID=27848 {ECO:0000313|Proteomes:UP000050740, ECO:0000313|WBParaSite:ECPE_0000330601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ECPE_0000330601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP69074.1, ECO:0000313|Proteomes:UP000272942}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Egypt {ECO:0000313|EMBL:VDP69074.1,
RC ECO:0000313|Proteomes:UP000272942};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAN01040272; VDP69074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183A8L8; -.
DR WBParaSite; ECPE_0000330601-mRNA-1; ECPE_0000330601-mRNA-1; ECPE_0000330601.
DR Proteomes; UP000050740; Unplaced.
DR Proteomes; UP000272942; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR037769; Abr/Bcr.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23182; BREAKPOINT CLUSTER REGION PROTEIN BCR; 1.
DR PANTHER; PTHR23182:SF1; RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000272942}.
FT DOMAIN 277..481
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 537 AA; 61289 MW; 247C408E1A8BB36A CRC64;
MYKFSYPQLT QISENTDPDI FFALLSSDLH ILCLTIIDSR LIGELALLSP QLILPVGDAQ
GRTHYILLVT EREREQWRVA MDTQKMHYQI LLYKTEQKPA PSTNTGTVEP VVTDSLARAQ
TLPNTSRAEP SQAEINELLK HYSQRELKLF KLNKTGTAIL HSYHVRIEVD SYGQYEEVAR
TRVVTRFADP EWHQTFDLHV DDAHQICFTI YRHCDYVGYV ELVLDRSNLS YSNEVRLIDT
HETGQKMIYF TFSLTFRERT FLKHDNIKQQ KEGIFSVPLM SLIKHEKQLR SKGGGKTPEP
LVPRIVTSCV DEIERRGLKE VGLYRICGAN SDIQTMITLF NQDQEEAIGR LPTLEISVIA
SVLKQFFRDL PEPLLTDEGS VALMAAVENP DENQRNKSLF DCISQLPTAN RDTFTFLATH
LITVARYKET NMMDLGNLAL IWSTAIFQTS SETLRIHTGV KITPGTGTYM DSLNREAAVG
FHQTKTLSII LTAAQTGKLK WPQRDGRRLG GREDPERGTR QCDSLKCVEQ VELFVER
//
