ID   A0A183B2H3_9TREM        Unreviewed;       792 AA.
AC   A0A183B2H3;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=MPN domain-containing protein {ECO:0000313|WBParaSite:ECPE_0001344701-mRNA-1};
GN   ORFNames=ECPE_LOCUS13408 {ECO:0000313|EMBL:VDP90680.1};
OS   Echinostoma caproni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Echinostomatidae;
OC   Echinostoma.
OX   NCBI_TaxID=27848 {ECO:0000313|Proteomes:UP000050740, ECO:0000313|WBParaSite:ECPE_0001344701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ECPE_0001344701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP90680.1, ECO:0000313|Proteomes:UP000272942}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Egypt {ECO:0000313|EMBL:VDP90680.1,
RC   ECO:0000313|Proteomes:UP000272942};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAN01055028; VDP90680.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A183B2H3; -.
DR   WBParaSite; ECPE_0001344701-mRNA-1; ECPE_0001344701-mRNA-1; ECPE_0001344701.
DR   Proteomes; UP000050740; Unplaced.
DR   Proteomes; UP000272942; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR   InterPro; IPR045153; Est1/Ebs1-like.
DR   InterPro; IPR000555; JAMM/MPN+_dom.
DR   InterPro; IPR037518; MPN.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR15696; SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7; 1.
DR   PANTHER; PTHR15696:SF40; TELOMERASE-BINDING PROTEIN EST1A; 1.
DR   Pfam; PF01398; JAB; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50249; MPN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000272942}.
FT   DOMAIN          729..792
FT                   /note="MPN"
FT                   /evidence="ECO:0000259|PROSITE:PS50249"
FT   REGION          90..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..462
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        463..490
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   792 AA;  88305 MW;  ECF607DD5E4A5554 CRC64;
     MRTLAASNPF PTASQSLAAL FNEIRPKAEN LMRQLRRPKA EATHSHHTSF HSTDPRFQRV
     EIWIHPVDGQ TTVLQGARRL VYLPATTSCG AQKGGPRSQV SLSDWDRVGD NDEDDEEAQA
     EQEEYANMSL IEALLRELFS VPINDLRLFS IATGNMETFP EVASVALQAL SGLLAQKPCP
     LSAERLCQLC LVNMYNVDRA MSLTTHVGSI SSTKDKNLGT KTGGVLDQLD RPLHSGIEVE
     LDRSKIQPIS RLSGSETLRS VHHDHAARFA LDAFSLLCRR TAQLLQEWMI LHPEHWLPPP
     NHRDPTLRPY LNDWQLVAEL CTRAANWLNR NSTRPEYEEV NPTTSLVLRL KGISEGENED
     GEKQSRDQLQ DFQAAFLFEE AYVAGFKPML DLVPKLYRYT GDWASETVAD FVRIEKLVLF
     GDFLCGIEPP VLTYDVNRSV YESAIERESS ERKQDRPLEP KHLNNSLDSN ESTPSSNEKN
     KPGVSSEMTD LNDSQASADI AALQLKRALL QRQLEEEARL AAWRRNAISQ AASGGRRAIE
     LEVRPIYLLP DTNCYIDWLE GIATLAQRSS NYTVLVPIVV VNELDTLARY GSSSSNGSTW
     RSGRLIEEDG EVTRAGLIQE RAHQAITYLE HESTNADCQG AHIMETEDVG ASVPDAASTL
     TERNDAQNEP TNIGQLNACT SAQAAWETEN NVETILGPVD EYFKYDVKAH QSIVNAKPWE
     KDPHYFKYIK ISAVALLKML IHARSGGNIE IMGVLIGKVA HQTMIVVDSS PLPVEGTETR
     VNAQVSFSYS LP
//