ID   A0A183BV94_GLOPA        Unreviewed;       930 AA.
AC   A0A183BV94;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Globodera pallida (Potato cyst nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC   Globodera.
OX   NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_000453200};
RN   [1] {ECO:0000313|Proteomes:UP000050741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA   Aslett M.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000050741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA   Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA   Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA   Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA   Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT   "The genome and life-stage specific transcriptomes of Globodera pallida
RT   elucidate key aspects of plant parasitism by a cyst nematode.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|WBParaSite:GPLIN_000453200}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC       {ECO:0000256|ARBA:ARBA00008792}.
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DR   AlphaFoldDB; A0A183BV94; -.
DR   WBParaSite; GPLIN_000453200; GPLIN_000453200; GPLIN_000453200.
DR   Proteomes; UP000050741; Unassembled WGS sequence.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF99; ATP-DEPENDENT RNA HELICASE DHX37-RELATED; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
FT   DOMAIN          147..255
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          294..528
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          335..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..29
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   930 AA;  105647 MW;  0DF22ABDC218F002 CRC64;
     MNLLTSIAGN KKENCNQKQK SEVVRKLRCV SDGPSKNGDL KQKQRNHIET DSSSCEEDLP
     ETNEQQPNRT EKCIKLQPVP KTINESEIYL LPAYEAQKIV DQPAEKNPAQ NASTKMVKQF
     ERKTKFSDDT LLRIKGRQIV VQRTESIETI NENPVVIICG ETGSGKTTQI PQFLYEAGYT
     SNGHLIGVTE PRRIAAISMA SRVGYELHDS KMASYQIRYE GNQSEETRIL FMTDGVLLKE
     LQRCVNRTSV KDLRCQNETW LPAETNNHVI NVEARQFPVT IYFERRTPNN YLEAVFKKVC
     KIHEEYPAGG ILVFVTGQRE VDHLVKLLGS KYRRTPSSSG RKRQLKKHCP THEEHDNKVE
     EAEEQMVFDN DEFGTYDMDD GNDEQNDGIF DDMQPFNTEQ PSTSSLFDKC PPLLPIPLYS
     LLPVHLQQRV FRETPEDGSR ICVISTNVAE TSLTIPNVRY VIDCGKEKRR EYDPVTGVSR
     HRPIKERVVP GAFSLDTHSV YEDMRDYSAP EILNKPIDQL ILMLKAMNFT KMGNFPFPTP
     PKLDQIKSAE LRLTQLGALK AQQDGLLSIT PLGQSLAQLP LAPAFAKVVV SSVRDGLLPY
     SVTLVSALSV REPLVSILSI KEEGGTDETR KRVSEMVKQR RLWCAIGEAR LFGDLTVILN
     IVGAADYASE NESTVKALGL RPKALKEINK QRNQLALILN RADSVKEKLP TEFRMDPPSQ
     EQLRKLRHIM VKCLPDKLAK KDSSPDAPKG AYKTQQLKDY VFIDENSVLH KEQPDYVLYQ
     EIVQLENKKC LKQLSSRSRT GRRETDFLQP TSKIASPATA CVIKNYFVTF GFVEQSDVGK
     AVQVVEYHLN GDIKARLIFT LAELREVYEL FVEETKLKIW LDTDCGLRVL RINHSTPLYG
     NLRPLVIPIY NLMEFVKQLE IVLMSEKLQD
//