ID A0A183C7L1_GLOPA Unreviewed; 721 AA.
AC A0A183C7L1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
OS Globodera pallida (Potato cyst nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC Globodera.
OX NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_000885700};
RN [1] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Aslett M.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT "The genome and life-stage specific transcriptomes of Globodera pallida
RT elucidate key aspects of plant parasitism by a cyst nematode.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:GPLIN_000885700}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC {ECO:0000256|ARBA:ARBA00005755}.
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DR AlphaFoldDB; A0A183C7L1; -.
DR WBParaSite; GPLIN_000885700; GPLIN_000885700; GPLIN_000885700.
DR Proteomes; UP000050741; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 1.10.287.690; Helix hairpin bin; 1.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR Gene3D; 3.40.960.10; VSR Endonuclease; 1.
DR InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR InterPro; IPR004868; DNA-dir_DNA_pol_B_mt/vir.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR PANTHER; PTHR33568; DNA POLYMERASE; 1.
DR PANTHER; PTHR33568:SF3; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF03175; DNA_pol_B_2; 2.
DR PRINTS; PR00106; DNAPOLB.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE 3: Inferred from homology;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT DOMAIN 207..382
FT /note="DNA-directed DNA polymerase family B
FT mitochondria/virus"
FT /evidence="ECO:0000259|Pfam:PF03175"
FT DOMAIN 403..517
FT /note="DNA-directed DNA polymerase family B
FT mitochondria/virus"
FT /evidence="ECO:0000259|Pfam:PF03175"
SQ SEQUENCE 721 AA; 82304 MW; 664D2793BC57252D CRC64;
MRKLFFNETF DDITDSVTIP SACMKCFVSM AHYDKQKIAI IPHLGYEKRG KQSCIARKYL
KWRAEEEMRE NGLTLRHVES PGGEYKFGNY SLDGMLERPE EGNNLAIEVN GCFWHACPHC
FPDDAAIVAG GETAGAIRAR DAKRIAHIAR EFEVEIIWEC HLNRLLEDDP AMKAFFDNTP
DSGPIDFHDA FFGGRTGPEW LGASAINAET GERLGKTIKI KDFNSLYPSR NMFTNYPVGH
PTLVHFDKDV HWCKPADMVG EDGDILEGII KCFVVPPRHV HCGIPVLPLR MNKRTLFPLC
RKCSELFPNG AVDREYSCPH FEDEERGFSV TIPHIELAEA LKAGYRVTRV FRAYIWPLAS
DWSPFLFHTY LEKFLKMKFE ASGYPANCSE EGLSEEEAAA RKKAYIDKAW SVCQVRLNPD
RIKYNAGMRY VSKLCLNSLW GRFALRNRLT KTEIIDNHSD LAKLLNDDKI EISSIDQLTE
KFWMVCYKAK DEHVVEHDTS NVALALWTTS AARIHLLDSL QKVFCAADGT ARKDTRVLYM
DTDSIFYEFE TALGDPLPGG EQLGELTDEY PSHTIVEFVC AGPKAYALWL RDNTTGEDQF
KMKLRGITLD SDACQHINYA KMKEMVMEKW GAVDNYCSFN YPTKNFRITK KGDIFTVPLT
KRFNPTVNKG VIRDEGLRVV PFGYTDREYC QLNNPHCCEC QVFVPDPEYY FNIADLGHES
D
//
