ID   A0A183C9J7_GLOPA        Unreviewed;      1054 AA.
AC   A0A183C9J7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:GPLIN_000954500};
OS   Globodera pallida (Potato cyst nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC   Globodera.
OX   NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_000954500};
RN   [1] {ECO:0000313|Proteomes:UP000050741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA   Aslett M.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000050741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA   Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA   Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA   Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA   Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT   "The genome and life-stage specific transcriptomes of Globodera pallida
RT   elucidate key aspects of plant parasitism by a cyst nematode.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|WBParaSite:GPLIN_000954500}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A183C9J7; -.
DR   WBParaSite; GPLIN_000954500; GPLIN_000954500; GPLIN_000954500.
DR   Proteomes; UP000050741; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF104; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        295..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        346..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        720..746
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        755..774
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        780..803
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        823..844
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        864..885
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        892..916
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          332..443
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          918..1027
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        918..975
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        976..995
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1054 AA;  117867 MW;  B69BCAF4CAE848F2 CRC64;
     MRHPTHLFEM AFNRLGSQIG KHPKLIIAGG VLFALLSSIG LLRFEEENNV RTEYSPLNAP
     SKKEYQVAKQ FLKQNGTLDP CYIMSRAHDG GNLLRDDYRW LLYNLTKSLQ QEVRVISGGR
     VFGYRDLCEP YCEMNTAFLA FLKVYDPTQP LTHTYPAMEM FGTRAFIGNN VYGVTLKNLS
     VDLSSIGADR AGENSSTTTE EERALLMALS VAEEGKKAHR QQQKNIKLLE AFTTAVMPFY
     LVSDYKDTEL LNKWQKAAVE LFERPQYSRL FKTGMTGDNM VTAEVRRMGV ETAPLLVGSV
     VAMIVFVLFT LIRVRKTENR LWEAFVGCLS SSIGLMSIAG WRFQSIIVAA LFLVLSVGVD
     DIFILMRAWQ RSNELYLIPE RMAQCLEDAG PSITISSLTN VISFIIGAFS DTPAVRTFCI
     FSAIAISICW LYQLVFLSAV LVFSEGRRQK TVAKGILKGP KSDGQEYCAM ASHGERLQRM
     IVEFWAWAVT KWFTRFVLTL FMSVYFFISW QGIQILQSNI SIDKMALPNS YLHQFQLQFE
     TALRNMQPIS VFVLRPGDLR DPQQLARVKQ LVWDFEHALN SYGAESTFFW LPQYEDFVRF
     YSSGNENEDE GEADPTEDRP PPFDYTEMPA FFRSASYFYL SSFVHHNESA CLANQPECIS
     SFFFVTNFHR VIKYHELVPT VREWRRIAQH YADMEVFAYS DHTPFVDQTM SIDQTVLGSV
     AAALLCTCMV CLVFIPHFLS VVAAVFSTMS IDQTVLGSVA AALLCTCMVC LVFIPHFLSV
     VAAVFSVFSI SCGIFGFLAL WGVDLGSLLK CPLALQITAS DPLSMAALLM AIGFSVDFTS
     HISYHYYKAP DGNAQVRMQH TLTVIGWPMV QVGLSTIVAL LPLLLKQSYL AMTIVVVVCL
     GMFHGLVILP AVLTALPSTE DSKSSSTSSS SHSSAHRRES SQSAKSSSGS SAASSDGGIG
     SEESSTSTSN TSLEGDSQSE RRRKATADGS TEADKRKMAN QNGTAGSVLF RMKPFDRKRE
     VPREENVNQN ASNGILWTEL FRWSVNGSPK HRRR
//