ID A0A183CHE2_GLOPA Unreviewed; 1329 AA.
AC A0A183CHE2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Extracellular matrix protein FRAS1 {ECO:0000313|WBParaSite:GPLIN_001229800};
OS Globodera pallida (Potato cyst nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC Globodera.
OX NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_001229800};
RN [1] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Aslett M.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT "The genome and life-stage specific transcriptomes of Globodera pallida
RT elucidate key aspects of plant parasitism by a cyst nematode.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:GPLIN_001229800}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC {ECO:0000256|ARBA:ARBA00005586}.
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DR WBParaSite; GPLIN_001229800; GPLIN_001229800; GPLIN_001229800.
DR Proteomes; UP000050741; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09919; SH2_STAT_family; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.20.1050.20; STAT transcription factor, all-alpha domain; 1.
DR Gene3D; 2.60.40.630; STAT transcription factor, DNA-binding domain; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001217; STAT.
DR InterPro; IPR048988; STAT_linker.
DR InterPro; IPR013800; STAT_TF_alpha.
DR InterPro; IPR015988; STAT_TF_coiled-coil.
DR InterPro; IPR013801; STAT_TF_DNA-bd.
DR InterPro; IPR012345; STAT_TF_DNA-bd_N.
DR PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR PANTHER; PTHR11801:SF43; SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR; 1.
DR Pfam; PF01017; STAT_alpha; 1.
DR Pfam; PF02864; STAT_bind; 1.
DR Pfam; PF21354; STAT_linker; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF47655; STAT; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 486..577
FT /note="STAT transcription factor all-alpha"
FT /evidence="ECO:0000259|Pfam:PF01017"
FT DOMAIN 633..775
FT /note="STAT transcription factor DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF02864"
FT DOMAIN 818..889
FT /note="Signal transducer and activator of transcription
FT linker"
FT /evidence="ECO:0000259|Pfam:PF21354"
SQ SEQUENCE 1329 AA; 149337 MW; 7CFC65B84448BE05 CRC64;
MQQQQLNECA KAYQECKPCG WANCIPDAGT AATACCAANY AFKCCTEKPP QTTPRQLEEL
EDCEKARKKC PYRMSSCIAK RGQAAGACCS QNQLFTCLEP SIVWDKKTAL ELLQDFQTNK
ECKAKSFCVC EGPYFPQNRG RFVGNVPHRL IGTCCDNSSA CQCCWTDKAI VKLPTLHKVA
KTKECKAMIV EEEKCNCAHA HHPYYPNLVP HSCVKEEVWS ASPCCKDGFR IECCAYPEMD
LQSHVARVLC DANDPKSDDC TAIGYYAAAG FDCEHAPEIN SICFFNFLVA RNVDKPIAIS
QKPVLTLCKG RAKECPCGHA SCVFTGLLAA SIDACCDGLY EFKCCANATA LTTTTAHPKG
IFEKGKCEDS TEIKRICKTC DFYSCIRREG YASSICCAEH YVMTCCVGEQ VPTSATKSTM
QTTMSKEVTT TMAKTTTMTK MSTNPMTKIT TTTTVEDPIY AERKAAGPPM QCLIKAICTM
EMQRRASHLY EQLTDRRANL VQRLNDGVQL IVLMQSQLIS ERLLDWKNSQ KLSQIGVVFE
QREQILDEIQ SEFEVLAENN WTLRACACWQ LDLLKRSPRL SDSQSVQSHI SNLTYILETL
TKLLVQNCKN CCTDYCRPVQ CMLVTQSFVV AVQPEPVLKT QHKFVAEVRL LIGERLGIKQ
QLINTNVTVK IIAEEEAKML STGQLNEKDI KTVGSISNDF EKLVLDERGH MAAKFNNSKL
SRIAHRKPPA KGSLQASQCA QTATDQKYAL LFHITPFQLG NLGKFDVWTL SLPIMDCDAQ
AVILWQRAFS SVVSDHSRQI PDNSLPDSQN RTNASDDVSM VAWPDLSRVL RHKFFLFTGA
NRPLSESDLA YLGEKLGMHS HGDNKPITFQ RFAKQNLRDD VNFSFWEWFF LIMQLIKQKL
LKFWDEGWLV GFISKQDTSS QMMMCPNLTF LLRFSDTQTG AVSIGFVCEE DGIKVPFHLA
PFTIKDLDQL SLASRIRNCP QLQEIRYLHP DIEKEEMLAY FESEEQRLRV NETSPTGYIG
SEIVMVAKTA GCKLNSALGS DSPSPMSNQW SPGELQQSNS MEISDDIVSI LSQNQLEAAN
VESLLGFQVG HRMAVDQQQP MPHLDLSFMD SFAVQPNAAQ CDVLDQLTKR GQALLVDARM
EGIEIRQCTC PEQTECIDEM QMQAIDCVKS CWTTFSAITD QPQKLRTCFV RADVLIDEFV
KCFENTVESC LQQREEKMIN KVNITEMFRL GIERIEKTKA QLLKSLADGP IKKIMDTTSK
FGVCVKDCFL AKNPNQYCFD EKDCQPLLVG AKATKSLRKC TKRIDWKKES GELCECSVKA
GIADMEQYW
//
