ID   A0A183CLG6_GLOPA        Unreviewed;       745 AA.
AC   A0A183CLG6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=RING-type domain-containing protein {ECO:0000313|WBParaSite:GPLIN_001372200};
OS   Globodera pallida (Potato cyst nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC   Globodera.
OX   NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_001372200};
RN   [1] {ECO:0000313|Proteomes:UP000050741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA   Aslett M.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000050741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA   Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA   Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA   Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA   Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT   "The genome and life-stage specific transcriptomes of Globodera pallida
RT   elucidate key aspects of plant parasitism by a cyst nematode.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|WBParaSite:GPLIN_001372200}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A183CLG6; -.
DR   WBParaSite; GPLIN_001372200; GPLIN_001372200; GPLIN_001372200.
DR   Proteomes; UP000050741; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0033130; F:acetylcholine receptor binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043495; F:protein-membrane adaptor activity; IEA:InterPro.
DR   GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR   CDD; cd16478; RING-H2_Rapsyn; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR019568; Rapsyn_myristoylation/link_N.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46574; 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE; 1.
DR   PANTHER; PTHR46574:SF1; 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE; 1.
DR   Pfam; PF10579; Rapsyn_N; 1.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          434..480
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          552..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          588..617
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          709..745
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          193..220
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        725..745
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   745 AA;  82229 MW;  C01F1DD1EFC6DE87 CRC64;
     MGNLLNIRAR HARSQMRHGI KLYQQQNPQQ AIRQWRAALR RLKSVEDKFI TIGYIVQAFC
     DSGEFEQMLY AAVEQVDLAN GHQDDFMKSE ALLNLARANE RLADFEKAIG YAESSLELPG
     IDRRSPGYAH LVMALAHMGM SNFQSSLQQF EKAMKIANAN TDKLLELQLS LGLGNLFTLM
     SVGLVMALAH MGMSNFQSSL QQFEKAMKIA NANADKLLEL QLSLGLGNLF TLMRDLNKAL
     VFLQNALGIL QGIEANHVHA KYKSAILFQL SVILRLKGRY SEAREVCEES MDLAKSVGNK
     PVFARALASL ADICRELGET EARETITKSW ARYEQAFRLL RKLNDRMGQV TVLAQMAKSA
     AENKGVHYAG RCECQAIQLN RKCLEMASLI GAKHPMMECH LRLQELYVQL SDNENAEQSV
     QAQCSLVQEM ELFCNFCGQR YGEADESLQA LSCSHIFHER CLQKIFARIG EGPTTCPKCR
     SRASLMENIS LSSSNAPTPA TESLAGEFVV SPLPAADPCT STAVATSEAQ TQHPPIPVVL
     CERNFDASRW NSISHSGAPS SSTTTTRMES AERRICLSTS TVSSTCSASF RRQVKSNGSS
     SAAKNGQNGR QQQQRPPIAL STFATSTQKE NALPTEHNDK DGTVWRSEFK EDNGAGGVGV
     VENISQPLSS LEGGAKLNHV DSCRRRKKAA VPSSAKGLLA IGRERMAAIS PVAEEEEEEE
     EDKAEDDERR RGREPTTRER GVTEL
//